摘要
目的探讨氯沙坦钾片联合黄葵胶囊和贝前列素钠片对腹膜透析患者腹透液蛋白丢失的影响。方法选取2018年3月~2019年8月我院收治的腹膜透析患者60例作为研究对象,均给予常规透析后加用氯沙坦钾片联合黄葵胶囊和贝前列素钠片,比较治疗前与治疗后3个月血浆白蛋白及腹膜透析液中总蛋白、微量蛋白水平。结果治疗后3个月,患者血浆白蛋白水平高于治疗前,总蛋白、微量蛋白水平低于治疗前,差异具有统计学意义(P<0.05)。治疗后不良反应发生率为6.67%(4/60)。结论氯沙坦钾片联合黄葵胶囊和贝前列素钠片治疗腹膜透析患者,可提高患者血浆白蛋白水平,降低腹膜透析液中总蛋白、微量蛋白水平,且不良反应轻微,对腹膜透析治疗效果具有一定促进作用。
Objective To investigate the effect of losartan potassium tablets combined with Huangkui capsules and beprost sodium tablets on protein loss of peritoneal fluid in patients with peritoneal dialysis.Methods 60 patients with peritoneal dialysis admitted in our hospital from March 2018 to August 2019 were selected as the research subjects.All patients were given losartan potassium tablets combined with Huangkui capsules and beprost sodium tablets after routine dialysis.And 3 months after treatment with plasma albumin and peritoneal dialysate total protein,trace protein levels.Results Three months after treatment,the patient's plasma albumin level was higher than that before treatment,and total protein and trace protein levels were lower than before treatment,the difference was statistically significant(P<0.05).The incidence of adverse reactions after treatment was 6.67%(4/60).Conclusion Losartan potassium tablets combined with Huangkui capsules and beprostone sodium tablets in patients with peritoneal dialysis can increase patients'plasma albumin levels,reduce total protein and trace protein levels in peritoneal dialysate,and have minor adverse reactions.The effect has a certain promoting effect.
作者
谢小街
黄凤梅
王满琴
杨尚凌
顾佳龙
陈建
XIE Xiao-jie;HUANG Feng-mei;WANG Man-qin;YANG Shang-ling;GU Jia-long;CHEN Jian(Department of Nephrology,the 908th Hospital of the Joint Logistics Support Force,Yingtan 335000,Jiangxi,China;Department of Critical Care Medicine,the 908th Hospital of the Joint Logistics Support Force,Yingtan 335000,Jiangxi,China)
出处
《医学信息》
2019年第24期136-137,共2页
Journal of Medical Information
基金
鹰潭市科技计划项目（编号：Ykz20180059）
关键词
腹膜透析
氯沙坦钾片
黄葵胶囊
贝前列素钠片
腹透液蛋白丢失
Peritoneal dialysis
Losartan potassium tablets
Huangkui capsules
Beprost sodium tablets
Peritoneal fluid protein loss
