摘要
目的研究在应用两性霉素B药物治疗时检验前周转时间对监测血清钾准确性的影响。方法对比含有两性霉素B药液的实验组和对照组在不同分离时间的血清钾浓度。结果同对照组相比含两性霉素B药液的实验组在分离时间≥60min以上时,血清钾浓度明显增高,并观察到实验组内随时间的延长血清钾浓度也呈明显增高,差异具有统计学显著性意义(P<0.001)。结论为保证检验结果的准确性,临床在应用两性霉素B药物治疗时监测血清钾浓度要避开血药峰时采血以及采集标本后30 min内分离血清或血浆立即测定。
Objective To study the effect of pretest turnaround time on the accuracy of serum kalium monitoring in amphotericin B drug therapy. Methods The serum kalium concentrations of amphotericin B solution were compared between the experimental group and the control group at different separation times. Results Compared with the control group, the serum kalium concentration in the experimental group containing amphotericin B solution increased significantly when the separation time was more than 60 min, and it was observed that the serum kalium concentration also increased significantly with the extension of time in the experimental group, with statistically significant difference(F=6.787~21.67,P<0.001). Conclusion In order to ensure the accuracy of the test results, the clinical monitoring of serum kalium concentration during amphotericin B therapy should avoid the blood sampling at the peak of blood drug and the immediate determination of serum or plasma within 30 minutes after sample collection.
作者
王麟
胡鹏
成景松
WANG Lin;HU Peng;CHENG Jing-song(Department of Clinical Laboratory,Chengdu Pidu District Hospital of Traditional Chinese Medicine,Chengdu 611730,China;Department of Clinical Laboratory,Baihe County People’s Hospital of Ankang City,Shaanxi Ankang 725800,China)
出处
《现代检验医学杂志》
CAS
2019年第6期123-125,共3页
Journal of Modern Laboratory Medicine
关键词
两性霉素B
血清钾
检验前周转时间
amphotericin B
serum kalium
turnaround time before inspection
