摘要
胆道癌在临床上较为少见,早期诊断困难,常规治疗手段疗效欠佳。作为时下新兴的研究热点,免疫疗法已被证实在多种癌症治疗中具备良好前景。目前包括免疫检查点抑制剂、过继免疫细胞治疗、肿瘤疫苗等在内的多种免疫疗法已经被运用于胆道癌的相关临床试验治疗中。现就免疫疗法在胆道癌治疗中的现状及展望进行简要阐述。
Biliary tract cancer(BTC)is rare in clinical practice and is difficult to diagnose in the early stage,and conventional treatment methods have unsatisfactory clinical effects.As a new research hotspot at present,immunotherapy has been proven to have a promising future in the treatment of a variety of cancers.At present,various immunotherapies,including immunological checkpoint inhibitors,adoptive immune cell therapy,and tumor vaccine therapy,have been applied in the clinical trials of BTC.This article briefly describes the current status and perspectives of immunotherapy in the treatment of BTC.
作者
罗奎
孙航
吴传新
LUO Kui;SUN Hang;WU Chuanxin(Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China)
出处
《临床肝胆病杂志》
CAS
北大核心
2019年第12期2837-2840,共4页
Journal of Clinical Hepatology
基金
国家自然科学基金面上项目(81871608)
关键词
胆道肿瘤
免疫疗法
治疗学
biliary tract neoplasms
immunotherapy
therapeutics
