摘要
目的探讨超声内镜(EUS)对胆总管结石的诊断价值。方法选取2017年6月-2019月4月就诊于安徽医科大学第一附属医院并疑诊胆总管结石患者98例。患者在院期间行EUS及磁共振胰胆管造影(MRCP)检查。以开腹探查/腹腔镜胆总管探查及经内镜逆行胰胆管造影/内镜下十二指肠乳头括约肌切开术结果为金标准。将EUS、MRCP及二者联合诊断(以EUS与MRCP任一阳性则为阳性,二者均阴性则为阴性)结果分别与金标准相比较,计算3种检查方法的灵敏度、特异度、阳性预测值、阴性预测值及诊断准确度。以上指标差别比较采用χ2检验。结果98例患者中EUS组阳性共92例,假阳性5例;阴性共6例,假阴性3例。MRCP组阳性69例,假阳性2例;阴性29例,假阴性23例。联合组阳性94例,假阳性5例;阴性4例,假阴性1例。EUS组灵敏度明显高于MRCP组(96.67%vs 74.44%,χ^2=17.982,P<0.05);EUS组与联合组灵敏度差异无统计学意义(96.67%vs 98.89%,χ^2=1.023,P=0.312)。微小结石(≤0.5cm)疑诊患者共52例,EUS组阳性51例,假阳性3例;阴性1例,假阴性1例。MRCP组阳性36例,假阳性1例;阴性16例,假阴性14例;联合组阳性52例,假阳性3例。EUS诊断灵敏度明显高于MRCP组(97.96%vs 71.43%,χ^2=13.303,P<0.05);EUS与联合检查灵敏度差异无统计学意义(97.96%vs 100%,P=1.0)。结论在诊断胆总管结石方面,EUS具有明显优势,尤其在胆总管微小结石中,EUS有较高的诊断价值,可作为有创操作前的首选检查方法。
Objective To investigate the value of endoscopic ultrasonography(EUS)in the diagnosis of common bile duct stones.MethodsA total of 98 patients who attended The First Affiliated Hospital of Anhui Medical University from June 2017 to May 2019 and were suspected of common bile duct stones were enrolled.All patients underwent EUS and magnetic resonance cholangiopancreatography(MRCP)during hospitalization.The results of open/laparoscopic common bile duct exploration and endoscopic retrograde cholangiopancreatography/endoscopic sphincterotomy were the gold standard for diagnosis.The results of EUS alone,MRCP alone,and EUS combined with MRCP(positive results of EUS or MRCP were considered positive,and negative results of both EUS and MRCP were considered negative)were compared with the gold standard,and the sensitivity,specificity,positive predictive value,negative predictive value,and diagnostic accuracy of the three methods were calculated.The chi-square test was used for comparison of the above indices.Results Of all 98 patients,92 had positive EUS results,among whom 5 had false positive results;6 had negative EUS results,among whom 3 had false negative results.Of all 98 patients,69 had positive MRCP results,among whom 2 had false positive results;29 had negative MRCP results,among whom 23 had false negative results.Of all 98 patients,94 had positive MRCP/EUS results,among whom 5 had false positive results;4 had negative MRCP/EUS results,among whom 1 had false negative results.The EUS group had a significantly higher sensitivity than the MRCP group(96.67%vs 74.44%,χ^2=17.982,P<0.05),while there was no significant difference in sensitivity between the EUS group and the combined group(96.67%vs 98.89%,χ^2=1.023,P=0.312).There were 52 patients who were suspected of biliary microlithiasis(≤0.5 cm),among whom 51 had positive EUS results,including 3 patients with false positive results;1 had false negative EUS results;among these 52 patients,36 had positive MRCP results,including 1 patient with false positive results;16
作者
崔喻芳
鲍峻峻
宋育林
张磊
梅俏
CUI Yufang;BAO Junjun;SONG Yulin(Department of Gastroenterology, The First Affiliated Hospital of Anhui Medical University, Hefei 230000, China)
出处
《临床肝胆病杂志》
CAS
北大核心
2019年第12期2741-2743,共3页
Journal of Clinical Hepatology
基金
安徽省教育厅高等学校省级质量工程教学研究项目课题(2015jyxm770)
关键词
胆总管结石病
腔内超声检查
胰胆管造影术
磁共振
诊断
choledocholithiasis
endosonography
cholangiopancreatography,magnetic resonance
diagnosis
