摘要
目的 回顾性分析32例淋巴瘤胃部浸润患者全身18F-FDG PET/CT检查结果,探讨淋巴瘤胃部浸润18F-FDG PET/CT显像特点及全身18F-FDG PET/CT检查在淋巴瘤胃部浸润诊断、分期、再分期和疗效评价中的价值。方法 选择2012年4月-2018年6月在福建省立医院被病理确诊为淋巴瘤胃部浸润并行18F-FDG PET/CT检查的32例患者作为研究对象,其中男18例,女14例,年龄24~83岁;3例患者胃淋巴瘤术后化疗前行PET/CT检查;另29例患者中8例患者治疗后行PET/CT检查评价疗效。釆用SPSS 17.0软件进行统计学分析。结果 (1)病理:经典型霍奇金淋巴瘤1例;非霍奇金淋巴瘤31例:B细胞淋巴瘤28例(弥漫大B细胞淋巴瘤18例,滤泡型B细胞淋巴瘤1例,套细胞淋巴瘤2例,Burkitt淋巴瘤1例,MALT淋巴瘤6例)。T细胞淋巴瘤2例,NK/T细胞淋巴瘤1例。(2)除3例胃部淋巴瘤术后患者外,29例中胃部病灶累及部位情况:全胃12例,胃体部4例、胃窦部7例,胃体+窦部4例,胃底+体部2例。(3)胃壁增厚厚度及SUVmax情况:0.9~3.2 cm,平均(1.71±0.66)cm,SUVmax 3.1~38.0,平均(13.83±9.06)。(4)无胃外其他部位淋巴瘤浸润11例;合并胃外其他部位淋巴瘤浸润21例:腹腔淋巴结浸润5例,回盲部肠管浸润2例,腹腔淋巴结及骨骼浸润1例,全身淋巴结多发浸润1例,全身淋巴结及多脏器浸润10例,腹膜浸润1例,甲状腺浸润1例。(5)胃外淋巴瘤浸润病灶SUVmax2.1~35.8,平均(12.30±8.98)。(6)3例胃淋巴瘤术后患者,2例未发现其他部位淋巴瘤浸润,1例发现其他部位淋巴瘤浸润。(7)8例化疗后复查,完全缓解(CR)6例,部分缓解(PR)2例。结论 淋巴瘤胃部浸润病灶部位放射性摄取较高,胃外脏器累及率高,18F-FDG PET/CT显像在淋巴瘤胃部浸润的诊断、分期及疗效评价中敏感性和特异性均较高,具有重要的临床应用价值。
Objective To retrospectively analyze the results of general 18 F-FDG PET/CT examination in 32 cases of lymphoma with gastric infiltration,and to explore the imaging features of 18 F-FDG PET/CT lymphoma patients with gastric infiltration and the value of systemic 18 F-FDG PET/CT in the diagnosis,staging,re-staging and efficacy evaluation of lymphoma with gastric infiltration.Methods From April 2012 to June 2018,32 patients who were pathologically diagnosed as lymphoma with gastric infiltration and underwent 18 F-FDG PET/CT scanning in Fujian provincial hospital were selected as study subjects,including 18 males and 14 females those who aged from 24 to 83 years old.PET/CT examination was conducted before postoperative chemotherapy in3 patients with gastric lymphoma.8 of the other 29 patients were evaluated by PET/CT examination after treatment.Statistical analysis was conducted by using spss17.0 software.Results Results of pathology:among the32 cases of patients,there was 1 case of typical Hodgkin lymphoma and 31 cases of non-hodgkin lymphoma.28 cases of the 31 cases were B-cell lymphoma(18 cases of diffuse large B-cell lymphoma,1 case of follicular Bcell lymphoma,2 cases of sleeve lymphoma,1 case of Burkitt lymphoma,and 6 cases of MALT lymphoma),two cases of T cell lymphoma and one case of NK/T cell lymphoma.In addition to 3 cases of patients with gastric lymphoma after operation,29 cases were involved in the gastric lesions:12 cases in the whole stomach,4 cases in the gastric body,7 cases in the gastric sinus,4 cases in the gastric body and sinus,and 2 cases in the gastric fundus and body.Thickening of gastric wall and SUVmax:0.9 cm^3.2 cm(1.71±0.66),SUVmax3.1~38.0(13.83±9.06).There were 11 cases of lymphoma infiltration only in the stomach.There were 21 cases of patients with lymphoma infiltration both in and outside the stomach:5 cases of peritoneal lymph node infiltration,2 cases of ileocecal bowel infiltration,1 case of peritoneal lymph node and bone infiltration,1 case of systemic lymph node multiple infil
作者
陈彩龙
林美福
陈文新
周硕
曹登敏
陈国宝
李君霞
CHEN Cai-long(Department of Nuclear Medicine of Fujian Provincial Hospital,Provincial Medical College of Fujian Medical University,Fujian,Fuzhou,350001,China.)
出处
《齐齐哈尔医学院学报》
2019年第20期2524-2526,共3页
Journal of Qiqihar Medical University
