摘要
目的探究彩色多普勒超声定量评估妊娠期高血压综合征(妊高征)心肌损伤状况的应用价值。方法选择2016年3月至2018年12月在东莞市人民医院进行产检并诊断为妊高征的78例孕妇作为妊高征组,另选择同期在本院进行产检的50例健康孕妇作为对照组。对两组孕妇进行彩色多普勒超声检查,观察比较两组孕妇的各左心房形态学参数、心功能状况以及心包积液发生情况。结果妊高征组患者的左房前后内径(LAD)、左房最大容积(LAV_(max))、左房最小容积(LAV_(min))、左房收缩前容积(LAV_(pre))水平均明显高于对照组,左房整体射血分数(LAEF)、左房主动射血分数(LAAEF)和左房被动射血分数(LAPEF)水平均明显低于对照组,差异有统计学意义(P<0.05)。妊高征组患者的左房整体纵向应变峰值(LA-GLPS)、左房收缩期应变率(LASRs)、左房舒张早期应变率(LASRe)水平均明显低于对照组(P<0.05),两组的左房舒张晚期应变率(LASRa)比较则无统计学意义(P>0.05)。妊高征组的心包积液发生率为15.38%,明显高于对照组(4.00%),差异有统计学意义(P<0.05)。结论多普勒彩色超声能够对妊高征孕妇的左心房形态和心功能状况作出定量评估,对于其心肌损伤的临床诊断具有重要意义。
Objective To explore the application value of color Doppler ultrasound in quantitative assessment of myocardial injury in pregnancy-induced hypertension(PIH)patients.Methods A total of 78 PIH women from March 2016 to December 2018 were selected and designed as PIH group,and 50 healthy pregnant women during the same time period were served as control group.The left atrial morphological parameters,cardiac function and pericardial effusion were observed and compared between two groups.Results The left atrial anteroposterior diameter(LAD),maximum left atrium volume(LAVmax),minimum left atrium volume(LAVmin),and left atrial pre-systolic volume(LAVpre)in PIH group were significantly higher than those in control group,while the left atrial ejection fraction(LAEF),left atrial active ejection fraction(LAAEF)and left atrial passive ejection fraction(LAPEF)were significantly lower than those in control group(all P<0.05).The left atrial(LA)global longitudinal peak strain(LA-GLPS),LA systolic strain rate(LASRs),LA early diastolic strain rate(LASRe)in PIH group were significantly lower than those in control group(P<0.05),but there was no significant difference on LA late diastolic strain rate(LASRa)between two groups(P>0.05).The incidence of pericardial effusion in PIH group was significantly higher than that in control group(15.38%vs 4.00%,P<0.05).Conclusion Doppler color ultrasound can quantitatively evaluate the left atrial morphology and cardiac function of PIH pregnant women and is important for clinical diagnosis of myocardial injury.
作者
陈巧琼
谢玉环
彭悦
CHEN Qiao-qiong;XIE Yu-huan;PENG Yue(Department of Ultrasound,Dongguan People’s Hospital Affiliated to Southern Medical University,Dongguan,Guangdong 523000,China)
出处
《中国临床研究》
CAS
2019年第12期1636-1638,1645,共4页
Chinese Journal of Clinical Research
基金
广东省医学科学技术研究基金(2016118233220266)~~
关键词
彩色多普勒超声
定量评估
妊娠期高血压综合征
心肌损伤
左心房功能
Color Doppler ultrasound
Quantitative assessment
Pregnancy-induced hypertension
Myocardial injury
Left atrial function
