摘要
抗血小板抗体自从问世以来,一直是研究血小板与血液成分和血管壁相互作用的重要工具.同时,抗血小板抗体在出血、血栓性疾病的检测和诊断方面也起着重要作用,并且成为一类强有力的抗血栓药物.随着对生理性止血和病理性血栓形成过程中血小板作用机制的深入理解,抗血小板、抗血栓抗体也在更好的抗栓效果和更小的出血不良反应之间找到平衡.
Since its inception, anti-platelet antibodies have been an important tool for studying the interaction of platelets with blood components and blood vessels. At the same time, anti-platelet antibodies also play an important role in the detection and diagnosis of hemorrhagic and thrombotic diseases, and become a kind of powerful anti-thrombotic drugs. With the further understanding of the role of platelets in physiological hemostasis and pathological thrombosis, anti-platelet and anti-thrombotic antibodies also seek a balance between better anti-thrombotic effects and less bleeding side effects.
作者
江森
季顺东
戴克胜
阮长耿
Jiang Miao;Ji Shundong;Dai Kesheng;Ruan Changgeng(Key Laboratory of Thrombosis&Hemostasis of National Health Commission of the People's Republic of China,the First Affiliated Hospital of Soochow University,Jiangsu Institute of Hematology,National Clinical Medical Research Center of Blood Diseases,Suzhou 215006,China)
出处
《白血病．淋巴瘤》
CAS
2019年第11期676-677,共2页
Journal of Leukemia & Lymphoma
关键词
血小板
抗体
血栓形成
Blood platelets
Antibodies
Thrombosis
