摘要
许多种宫缩抑制剂在当前临床治疗早产中得到广发应用,宫缩抑制有硫酸镁、β2受体激动剂、钙通道阻滞剂、宫缩受体拮抗剂等。据有关研究表明β2受体激动剂应用于早产中副作用较大,目前各大医院妇科正在减少此类药物的使用量,硫酸镁是西方国家临床妇科常用的宫缩抑制剂,国外大量文献研究发现该药物能够保护早产儿神经,而钙通道阻滞剂是近三年来受到了许多的关注,与β2受体激动剂效果相比,钙通道阻滞剂治疗更安全,但宫缩受体拮抗剂临床效果优于以上三种药物,具有用药安全性高、药价低廉、使用简单的特点。本文旨在对近年来宫缩抑制剂治疗早产的研究进展做简单综述。
Many kinds of uterine contraction inhibitors are widely used in current clinical treatment of preterm labor. The tocolytic inhibitors include magnesium sulfate, β2 receptor agonists, calcium channel blockers, and contraction receptor antagonists. According to relevant research, β2 receptor agonists have a large side effect in preterm labor. At present, gynecology in major hospitals is reducing the use of such drugs. Magnesium sulfate is a commonly used tocolytic agent in clinical gynecology in Western countries. The drug can protect the nerves of premature infants, and calcium channel blockers have received much attention in the past three years. Compared with the effect of β2 receptor agonists, calcium channel blockers are safer to treat, but the contraction receptors The clinical effect of the antagonist is better than the above three drugs, and has the characteristics of high drug safety, low drug price and simple use. This article aims to briefly review the recent progress in the treatment of preterm labor with tocolytic agents.
作者
刘义环
LIU Yihuan(Department of Obstetrics and Gynecology,Dagang Hospital,Binhai New Area,Tianjin 300270,China)
出处
《继续医学教育》
2019年第12期152-155,共4页
Continuing Medical Education
关键词
宫缩抑制剂
早产
产妇
新生儿
子宫
contraction inhibitor
premature delivery
maternal
newborn
uterus
