摘要
精神分裂症属于重性精神疾病的一种,为患者和社会带来沉重的负担。精神分裂症的病因尚不清楚,诊断也存在争议。外泌体中的RNA(exoRNA)的表达随着机体生理、病理状况的改变而改变,能够反映机体的生理或病理状态,将它作为精神分裂症的潜在生物标志物,有助于走出目前疾病诊断的困境。本文就精神分裂症相关的exoRNA的研究进展与价值进行了归纳总结。
Schizophrenia is one of the most common kind of mental diseases that places a heavy burden on patients and society.Except that the etiology of schizophrenia is not clear,the diagnosis is also controversial.The expression of RNA in the exosome(exoRNA)can reflect the physiological or pathological states of the body and can used as a potential biomarker of schizophrenia.It will help current diagnosis of schizophrenia go out of the plight.The paper will present and summarize the research progress and values of exoRNAs related to schizophrenia.
作者
贺宽军
郭闯
He Kuanjun;Guo Chuang(College of Life Science,Inner Mongolia University for Nationalities,Tongliao,Inner Mongolia,028043,China)
出处
《当代医学》
2020年第1期188-191,共4页
Contemporary Medicine
基金
国家自然科学基金（81501151,81660234)
