摘要
心搏骤停无论在国内还是国外均是不可忽视的重大问题,其存活率目前仍较低.肾上腺素作为主要的心肺复苏(CPR)药物,在临床上的使用时间已超过半个世纪,但目前对其仍存在许多争议之处,如增加恶性心律失常的风险,可能降低长期存活率及神经功能预后良好率等.通过对肾上腺素在CPR应用中的发展历史、作用机制及近些年来的研究进展等进行综述,以期能够对肾上腺素有更加全面的认识,并为如何进一步合理使用肾上腺素提供新的思考.
Objective Cardiac arrest is a major problem that cannot be ignored both at home and abroad.So far,cardiac arrest survival rates are very low.Epinephrine has been used as a major cardiopulmonary resuscitation(CPR)drug for more than half a century,but there are still many controversies about it,such as increasing the risk of malignant arrhythmia,reducing the long-term survival rate and good prognosis rate of neurological function.The history,mechanism and research progress of epinephrine in CPR is reviewed to provide a more comprehensive understanding of epinephrine and new ideas about epinephrine reasonable usage.
作者
唐卉
周满红
Tang Hui;Zhou Manhong(Department of Emergency,Affiliated Hospital of Zunyi Medical University,Zunyi 563003,Guizhou,China)
出处
《中国中西医结合急救杂志》
CAS
CSCD
北大核心
2019年第5期632-634,共3页
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
基金
贵州省研究生教育创新计划项目(黔教合YJSCXJH〔2018〕092)
贵州省教育厅自然科学研究项目(GZZ2017006)。
关键词
心搏骤停
心肺复苏
肾上腺素
Cardiac arrest
Cardiopulmonary resuscitation
Epinephrine
