摘要
目的:分析听神经瘤患者与正常听力者、感音神经性聋患者之间的时域间隔感知能力的差异性,为听神经瘤临床研究提供诊断参考。方法:选取来临床听力诊断中心已确诊的听神经瘤组患者22例,正常听力组30例,感音神经性听力损失组16例,分别为各组受试者进行听觉时域间隔感知阈值测试(TGDT)。结果:听力正常组平均TGDT阈值为(3.56±0.82) ms,感音神经性听力损失组的TGDT阈值为(3.91±1.46) ms,听神经瘤组健侧TGDT阈值为(4.01±1.86) ms;听神经瘤组患侧TGDT阈值为(9.48±9.46) ms。经统计学分析,最大言语识别率和时域间隔察觉阈测试除外感音神经性听力损失组与正常听力组差异无统计学意义,听神经瘤组患侧与其他各组间均差异有统计学意义(P<0.05);TGDT阈值与PBmax不存在线性相关(P>0.05)。正常组TGDT阈值在性别、耳别上差异无统计学意义。结论:听神经瘤患者健侧耳的时间间隙响应阈未受影响,较正常人无明显改变。TGDT与最大言语识别率结果有较好的一致性,听神经瘤患者患侧耳的时间间隔响应能力较正常人显著减弱,言语识别率联合TGDT有助于蜗后病变的诊断。
Objective: We aimed to provide a basis for the clinical study of acoustic neuroma through investigating the ability of temporal gap detection in acoustic neuroma patients and comparing the abilities with those in people with normal and impaired hearing. Method: Twenty-two patients with confirmed acoustic neuroma, 30 normal hearing patients and 16 patients with sensorineural hearing loss were enrolled in this study, and the interval threshold for awareness of each group was tested. Result: The mean temporal gap detection test(TGDT) threshold of the normal hearing group was(3.56±0.82) ms;the sensorineural hearing loss group’s was(3.91±1.46) ms;TGDT threshold of healthy side of acoustic neuroma patients was(4.01±1.86) ms;TGDT threshold of the impaired side of acoustic neuroma patients was(9.48±9.46)ms. After statistical analysis, we found that excepting for the test of phonetically balanced maximum(PBmax) and TGDT, other results in the sensorineural hearing loss group and normal hearing group is of no statistical difference. The difference between the affected side of the acoustic neuroma group and the other groups was statistically significant(P<0.05). There was no linear correlation between the value of TGDT threshold and PBmax(P> 0.05). TGDT value of normal people has no significant difference among people of different genders and ears of different individuals.Conclusion: The TGDT of the healthy ear of the patients with acoustic neuroma is not affected, and there is no significant change compared with normal people. The TGDT test has a good consistency with the PBmax results. The time interval response ability of the affected ear of the acoustic neuroma is significantly weaker than that of the normal person. The combined test of PBmax and TGDT will contribute to the diagnosis of retrocochlear disease.
作者
兰兰
邵莲美
熊芬
谢林怡
于澜
韩冰
王秋菊
LAN Lan;SHAO Lianmei;XIONG Fen;XIE Linyi;YU Lan;HAN Bing;WANG Qiuju(Department of Otorhinolaryngology Head and Neck Surgery,General Hospital o£Chinese People's Liberation Army,Beijing,100853,China;Otolaryngology Clinical Hearing Center,Shenzhen Hospital of Southern Medical University)
出处
《临床耳鼻咽喉头颈外科杂志》
CAS
北大核心
2019年第11期1053-1056,共4页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
基金
国家自然科学基金重点项目(No:81530032,81830028)
国家重大科学研究计划项目(No:2014CB943001)
