摘要
[目的]研究肺炎支原体感染并发消化系统损害患儿的有关特征及发病因素的Logistic回归分析。[方法]选取2015年2月~2018年9月于我院接受诊治的肺炎支原体患儿200例作为纳入对象。将患儿是否并发消化系统损害分为消化系统损害组64例以及无消化系统损害组136例。分析消化系统损害组患儿的临床表现特征,对比2组患儿的基本资料以及起始抗生素应用时间、CRP、红细胞沉降率水平的差异。并通过Logistic回归分析肺炎支原体感染并发消化系统损害的影响因素。[结果]64例肺炎支原体感染并发消化系统损害患儿的恶心呕吐、腹痛、腹泻、急性胰腺炎、急性胆囊炎、急性肝炎、肝脾肿大的发生率分别为18.75%、15.63%、14.06%、6.25%、3.13%、1.56%、3.13%。消化系统损害组患儿发热持续时间≥7 d、发热程度为高热人数占比均高于无消化系统损害组(均P<0.05)。消化系统损害组患儿起始抗生素应用时间低于无消化系统损害组(P<0.05);而2组CRP、红细胞沉降率水平比较差异无统计学意义。经Logistic回归分析可得:肺炎支原体感染并发消化系统损害患儿的独立危险因素为发热持续时间、发热程度、起始抗生素应用时间(均P<0.05)。[结论]肺炎支原体感染并发消化系统损害患儿的主要临床表现囊括恶心呕吐、腹痛、腹泻等,其中发热持续时间、发热程度、起始抗生素应用时间均是肺炎支原体感染并发消化系统损害患儿的独立危险因素,临床工作中应针对上述因素予以相关干预,继而达到降低消化系统损害发生风险的目的。
[Objective]To study the Logistic regression analysis of related characteristics and pathogenic factors in children with mycoplasma pneumoniae infection complicated with digestive system damage.[Methods]200 children with mycoplasma pneumoniae who were received treatment in our hospital from February 2015 to September 2018 were selected as subjects.All children were divided into 64 cases of digestive system damage group and 136 cases of non-digestive system damage group.The clinical manifestations and characteristics of children in the digestive system damage group were analyzed,and the differences in the basic data of the two groups as well as the time of initiation of antibiotics,CRP and erythrocyte sedimentation rate were compared.Logistic regression was used to analyze the influencing factors of mycoplasma pneumoniae infection complicated with digestive system damage.[Results]The incidence of nausea,vomiting,abdominal pain,diarrhea,acute pancreatitis,acute cholecystitis,acute hepatitis,hepatosplenomegaly was 18.75%,15.63%,14.06%,6.25%,3.13%,1.56%,3.13% in 64 cases of mycoplasma pneumoniae infection complicated with digestive system damage.The proportion of children in the digestive system injury group with fever duration ≥7 d and fever degree of high fever was higher than those in the non-digestive system injury group(all P<0.05).The duration of antibiotic initiation in the group with digestive system damage was lower than that in the group without digestive system damage(P<0.05).However,there was no significant difference in CRP and erythrocyte sedimentation rate between the two groups.Logistic regression analysis showed that the independent risk factors of mycoplasma pneumoniae infection complicated with digestive system damage in children were duration of fever,degree of fever and time of initiation of antibiotics(all P<0.05).[Conclusion]Children with mycoplasma pneumoniae infection complicated with digestive system damage of major clinical manifestations include nausea and vomiting,abdominal pain,diarrhea
作者
陈丙文
陈斌斌
陈彩平
CHEN Bin-wen;CHEN Bin-bin;CHEN Cai-ping(Department of Pediatrics»Shenzhen Bao'an District Central Hospital,the Fifth Affiliated Hospital of Shenzhen University,Shenzhen 518000,China)
出处
《中国中西医结合消化杂志》
CAS
2019年第12期916-919,924,共5页
Chinese Journal of Integrated Traditional and Western Medicine on Digestion
