摘要
目的为降低慢性肾病患者的血液透析出现复发性栓塞性卒中的发生率,提高降低慢性肾病患者血液透析效果。方法选取自2017年5月至2018年5月间在海南医学院第一附属医院血液科进行血液透析的慢性肾病患者67例作为研究对象,所有的患者根据是否出现复发性栓塞性卒中分为研究组和对照组,检测两组患者血压及相关生化指标,并检测颈动脉粥样硬化情况,分析血液透析相关的危险因素与复发性栓塞性卒中发生的相关性。结果研究组患者收缩压(SBP)高于对照组(P<0.05),研究组患者LDL-C、Alb、hs-CRP水平明显高于对照组(P<0.05),研究组患者颈动脉粥样硬化及颈动脉斑块的发生率、颈内动脉内膜中层厚度(IMT)及颈动脉阻力指数均高于对照组(P<0.05),高血压、平均血透龄、血脂异常、颈动脉粥样硬化、体重增长均为脑卒中的危险因素。结论慢性肾病患者的血液透析、高血压、血脂异常、颈动脉粥样硬化、体重增长为复发性栓塞性卒中产生的危险因素。
Objective To reduce the incidence of recurrent embolic stroke in hemodialysis patients with chronic kidney disease, and improve the hemodialysis effect of patients with chronic kidney disease. Methods Sixty-seven patients with chronic kidney disease who underwent hemodialysis from the Department of Hematology of the First Affiliated Hospital of Hainan Medical University from May 2017 to May 2018 were enrolled. All patients were divided into study group and control group according to whether recurrent embolic stroke occurred. Blood pressure and related biochemical indicators were measured in both groups, and carotid atherosclerosis was detected. The correlation between hemodialysis-related risk factors and recurrent embolic stroke was analyzed. Results The systolic blood pressure(SBP) of the study group was higher than that of the control group(P<0.05). The levels of LDL-C, Alb and hs-CRP in the study group were significantly higher than those in the control group(P<0.05). The incidence of carotid atherosclerosis, carotid plaque, carotid intima-media thickness(IMT) and carotid resistance index were higher in the study group than in the control group(P<0.05). Hypertension, mean hemodialysis, dyslipidemia, carotid atherosclerosis, and weight gain were all risk factors for stroke. Conclusion Hemodialysis, hypertension, dyslipidemia, carotid atherosclerosis, and weight gain in patients with chronic kidney disease are risk factors for recurrent embolic stroke.
作者
陈娟
陈拉斯
唐文庄
陈惠
韦泽丰
CHEN Juan;CHEN Lasi;TANG Wenzhuang;CHEN Hui;WEI Zefeng(Department of Blood Purification,The First Affiliated Hospital of Hainan Medical University,Haikou 570102,China)
出处
《公共卫生与预防医学》
2019年第6期118-121,共4页
Journal of Public Health and Preventive Medicine
关键词
慢性肾病
血液透析
复发性栓塞性卒中
危险因素
Chronic kidney disease
Hemodialysis
Recurrent embolic stroke
Risk factors
