摘要
目的探讨白蛋白联合血浆输注对肾综合征出血热休克患者休克持续时间及肾功能的影响。方法按照随机数字表法将本院肾综合征出血热休克患者100例分为2组,每组各50例。对照组采用常规治疗,观察组采用白蛋白联合血浆输注治疗,比较2组患者休克持续时间、肾功能情况、炎性因子水平、并发症发生率。结果观察组休克持续时间短于对照组,差异有统计学意义(P<0.01);治疗后,观察组尿素氮(BUN)、血肌酐(SCr)水平低于对照组,差异有统计学意义(P<0.05);治疗后,观察组白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)水平低于对照组,差异有统计学意义(P<0.05);观察组渗出性肺炎、继发菌血症、多器官出血发生率低于对照组,差异有统计学意义(P<0.05)。结论白蛋白联合血浆输注治疗可缩短肾综合征出血热休克患者的休克持续时间,提高肾功能,减轻炎症反应,减少并发症。
Objective To investigate the effect of albumin combined with plasma transfusion on duration of shock and renal function in patients with hemorrhagic fever shock with renal syndrome.Methods A total of 100 patients with hemorrhagic fever shock with renal syndrome in the hospital were divided into two groups by random number table method,with 50 cases in each group.Control group was given routine treatment,and observation group was treated with albumin combined with plasma transfusion.The duration of shock,renal function,inflammatory factors,incidences of complications were compared between two groups.Results The duration of shock in observation group was shorter than that in control group,and the difference was statistically significant(P<0.01);after treatment,the levels of blood urea nitrogen(BUN)and serum creatinine(Scr)in observation group were lower than those in control group(P<0.05);after treatment,the levels of interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α)in observation group were lower than those in control group(P<0.05);the incidences of exudative pneumonia,secondary bacteremia,multiple organ hemorrhage in observation group were lower than that in control group(P<0.05).Conclusion Albumin combined with plasma transfusion for patients with hemorrhagic fever shock with renal syndrome can shorten duration of shock,improve renal function,relieve inflammatory response,and reduce complications.
作者
宋红波
李燕平
康立
贾小洲
王凤兰
张晨
李雪婷
SONG Hongbo;LI Yanping;KANG Li;JIA Xiaozhou;WANG Fenglan;ZHANG Chen;LI Xueting(Department of Infectious Diseases,Xi′an Eighth Hospital,Xi′an,Shanxi,710061)
出处
《实用临床医药杂志》
CAS
2019年第22期34-36,39,共4页
Journal of Clinical Medicine in Practice
关键词
肾综合征出血热休克
白蛋白
血浆
肾功能
休克持续时间
hemorrhagic fever shock with renal syndrome
albumin
plasma
renal function
duration of shock
