摘要
目的:探讨注射用A型肉毒毒素联合曲安奈德加5-FU联合注射治疗下颌角痤疮后增生性瘢痕的疗效。方法:选择2015年10月-2017年10月笔者科室诊治的30例下颌角痤疮后增生性瘢痕患者,均接受A型肉毒毒素联合曲安奈德加5-FU联合注射,增生性瘢痕面积0.3cm×0.5cm^2.0cm×3.0cm,高度0.5~1.5cm,评估咬肌肥大程度及颈阔肌紧张程度。使用注射用A型肉毒毒素注射咬肌及下颌缘,使用曲安奈德加5-FU行皮损内低压注射1次。间隔2周或3个月间断行皮损内低压注射,直至无复发情况出现。治疗后随访12~24个月,评价疗效。结果:30例患者均全部缓解,18例患者治疗1~2次后瘢痕完全萎缩,无复发情况;11例患者注射4~6次后瘢痕萎缩,随访1年,无复发情况;1例患者注射13次,随访1年,无复发。结论:注射用A型肉毒毒素联合曲安奈德加5-FU联合注射是治疗下颌角痤疮后增生性瘢痕较好的方法。
Objective To investigate the efficacy of injection of botulinum toxin type A combined with triamcinolone acetonide plus 5-Fu in the treatment of scar after mandibular acne.Methods From October 2015 to October 2017,30 patients with scar after mandibular angle acne were injected with botulinum toxin type A combined with triamcinolone acetonide plus 5-Fu.The area of keloid was 0.3cm×0.5cm-2.0cm×3.0cm,height 0.5-1.5cm,assess the degree of masseter muscle hypertrophy and platysma muscle tension.The masseter muscle and the mandibular margin were injected with botulinum toxin type A for injection,and intralesional low pressure injection of triamcinolone acetonide 5-FU was used once.The intralesional lowpressure injection was broken between 2 weeks or 3 months until no recurrence occurred.Follow-up was followed up for 12 to 24 months to evaluate the efficacy.Results All the 30 patients were all relieved.In 18 patients,the scar was completely atrophied after 1-2 treatments,and there was no recurrence.11 patients had scar atrophy after 4-6 injections,followed up for 1 year,no recurrence.One patient was injected 13 times and followed up for 1 year without recurrence.Conclusion Injection of botulinum toxin type A combined with triamcinolone acetonide plus 5-FU is a good method for the treatment of scar after acne in mandibular margin.
作者
张怡
赵小晖
吴信峰
ZHANG Yi;ZHAO Xiao-hui;WU Xin-feng(Department of Plastic surgery,Dermatology Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Nanjing 210042,Jiangsu,China)
出处
《中国美容医学》
CAS
2019年第12期53-55,共3页
Chinese Journal of Aesthetic Medicine
关键词
下颌角瘢痕
皮损内注射
注射用A型肉毒毒素
曲安奈德
低压注射
mandibular angle scar
intralesional injection
botulinum toxin A for injection
triamcinolone acetonide
low pressure injection
