摘要
目的探讨影像学在鉴别骨旁低度恶性型骨肉瘤与骨旁去分化骨肉瘤的应用价值.方法选取2013年1月至2018年1月本院收治的经术后病理检查确诊为骨旁低度恶性型骨肉瘤患者(n=68)及骨旁去分化骨肉瘤患者(n=35)为研究对象.采用统计学软件分析两组患者的临床资料(年龄、性别),肿瘤特征(肿瘤直径、日光照射征、是否坏死、周边钙化、钙化等级),周边组织情况(周边组织水肿、关节侵犯、血管侵犯、骨膜反应、骨髓水肿、骨髓侵犯),转移征象(骨转移、术前及术后肺转移),是否复发等资料.并将差异有统计学意义(P<0.05)的指标做ROC曲线,并计算曲线下面积.结果骨旁低度恶性型骨肉瘤组与骨旁去分化骨肉瘤组的最大平均直径分别为(7.0±1.2)cm、(10.5±1.9)cm,差异有统计学意义(P<0.05);日光照射征在骨旁低度恶性型骨肉瘤组与骨旁去分化骨肉瘤中的发生率分别为10.28%、68.57%,差异有统计学意义(P<0.05);骨旁低度恶性型骨肉瘤组与骨旁去分化骨肉瘤组术后肺转移的发生率分别为1.47%、(7/35)20%,差异有统计学意义(P<0.05);骨旁低度恶性型骨肉瘤组与骨旁去分化骨肉瘤组肿瘤直径及日光照射征曲线下面积分别为0.73、0.76.结论骨旁去分化骨肉瘤肿瘤组较骨旁低度恶性型骨肉瘤组直径更大,日光照射征的发生率也更高,并且骨旁去分化骨肉瘤更易发生术后肺转移.影像学在鉴别两者时可起到重要作用.
Objective To investigate the application value of imaging in differentiating low-grade paraspinal malignant osteosarcoma from para- spinal dedifferentiated osteosarcoma. Methods From January 2013 to January 2018, patients diagnosed with low-grade paraspinal malignant osteo- sarcoma (n=68) and patients with paraspinal dedifferentiated osteosarcoma (n=35) were selected as study subjects. Using statistical software analysis of two groups of patients with general information (age, gender), tumor characteristics (tumor diameter, sunlight, whether necrosis, peripheral calcifi- cation, calcified grades), peripheral tissue situation (peripheral tissue edema, joint infringement, vascular invasion, periosteal reaction and bone mar- row edema and bone marrow involvement), transfer signs (bone metastases, preoperative and postoperative pulmonary metastasis), recurrence of whether such information. The ROC curve was used for indicators with statistically significant difference (P<0.05), and the area under the curve was calculated. Results The maximum mean diameter of low-grade malignant osteosarcoma group and para-dedifferentiated osteosarcoma group was (7.0±1.2) cm and (10.5±1.9) cm, respectively, with statistically significant difference (P<0.05). The incidence rates of low-grade malignant os- teosarcoma and para-osteosarcoma were 10.28% and 68.57%, respectively, with statistically significant difference (P<0.05). The incidence of post- operative lung metastasis was 1.47% and 20% (7/35) (P<0.05), respectively, in the group with low-grade para-malignant osteosarcoma and the group with para-de-differentiated osteosarcoma. The tumor diameter and the area under the solar radiation sign were 0.73 and 0.76 respectively in the low-grade malignant osteosarcoma group and the para-dedifferentiated osteosarcoma group. Conclusion Para-osteosarcoma tumor group has larger diameter and higher incidence of solar radiation sign than para-para-malignant osteosarcoma group, and para-osteosarcoma is more prone to postoper- ative lung metasta
作者
吴志斌
Wu Zhibin(Department of Radiography,Fuzhou Second Hospital Affiliated of Xiamen University,Fuzhou,Fujian,350000,China)
出处
《当代医学》
2019年第35期109-112,共4页
Contemporary Medicine
关键词
骨旁骨肉瘤
低度恶性型
去分化
MRI
X光
影像学
Paraosteosarcoma
Low-grade malignant type
Dedifferentiation
MRI
X-ray
Radiography
