摘要
目的:观察使用不同剂量甲基强的松龙对百草枯中毒患者的临床治疗效果。方法:选取2017年2月-2019年2月在笔者所在医院治疗的86例百草枯中毒患者,按照剂量不同将患者分为试验组(40例)及常规组(46例)。常规组患者给予小剂量的甲基强的松龙治疗,试验组患者给予大剂量甲基强的松龙治疗。比较两组治疗效果。结果:两组病死率及脏器损伤情况比较,差异均无统计学意义(P>0.05)。试验组并发症发生率较常规组低,差异有统计学意义(P<0.05)。试验组治疗总有效率高于常规组,差异有统计学意义(P<0.05)。结论:百草枯中毒患者使用大剂量甲基强的松龙治疗,有助于降低患者并发症发生率,提升疾病临床治疗效果。
Objective: To observe the clinical therapeutic effect of different doses of Methylprednisolone on paraquat poisoning patients. Method: From February 2017 to February 2019, 86 patients with paraquat poisoning treated in our hospital were selected. They were divided into the experimental group(40 cases) and the routine group(46 cases) according to different doses. The routine group was given low dose of Methylprednisolone, while the experimental group was given high dose of Methylprednisolone. The therapeutic effects of the two groups were compared. Result: There was no statistically significant difference in mortality and organ injury between the two groups(P>0.05). The incidence of complications in the experimental group was lower than that in the conventional group, and the difference was statistically significant(P<0.05). The total effective rate of treatment in the experimental group was higher than that in the conventional group, and the difference was statistically significant(P<0.05). Conclusion: The treatment of paraquat poisoning patients with large dose of Methylprednisolone is helpful to reduce the incidence of complications and improve the clinical treatment effect.
作者
张冰
王莎莎
ZHANG Bing;WANG Shasha(Binzhou Medical University Hospital,Binzhou 256600,China)
出处
《中外医学研究》
2019年第33期41-43,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
百草枯中毒
甲基强的松龙
地塞米松
脏器损伤
并发症
治疗效果
Paraquat poisoning
Methylprednisolone
Dexamethasone
Organ injury
Complications
Therapeutic effect
