摘要
目的观察分析丙泊酚与七氟烷对老年肺癌患者术后认知功能的影响。方法方便选取该院2018年1月-2019年1月收治的120例老年肺癌行单纯性右肺下叶切除术患者为该次研究对象,按照患者术中麻醉给药不同将所有患者分为A组(60例:丙泊酚)与B组(60例:七氟烷),比较两组围手术期相关观察项目。结果 A组术后2、24 h简易智力状态检测量表(MMSE)同期评分(28.01±1.02)分、(29.52±0.42)分均优于B组(27.62±1.01)分、(28.62±0.43)分(t=2.278、2.286,P<0.05)。A组患者术后24 h呼吸指数(RI)(0.63±0.12)次/min以及血清S100β蛋白(82.71±5.35)pg/mL等相关数值均优于B组(0.86±0.13)次/min、(152.03±5.33)pg/mL(t=10.871、11.521,P<0.05)。结论老年肺癌行单纯性右肺下叶切除术患者术中丙泊酚麻醉给药效果明显优于七氟烷麻醉效果。
Objective To observe the effects of propofol and sevoflurane on postoperative cognitive function in elderly patients with lung cancer. Methods 120 elderly patients with lung cancer underwent simple right lower lobe resection in the hospital from January 2018 to January 2019 were Convenient selected into the study. All patients were divided into group A(60 cases: propofol) and group B(60 cases: sevoflurane) according to the intraoperative anesthetic administration, compared with the perioperative related observation items. Results In group A, 2 h after operation and 24 h postoperatively, the scores of simple intelligence state(MMSE) were(28.01±1.02)points and(29.52±0.42)points, which were better than those in group B(27.62±1.01)points,(28.62±0.43)points(t=2.278, 2.286, P<0.05). In group A, the respiratory index(RI) of(0.63±0.12) times/min and serum S100β protein(82.71±5.35) pg/mL were better than those of group B,(0.86±0.13) times/min and(152.03±5.33) pg/mL(t=10.871, 11.521, P<0.05). Conclusion The effect of intraoperative propofol anesthesia in elderly patients with simple right lower lobe resection is superior to that of sevoflurane.
作者
王兴耀
周臣
WANG Xing-yao;ZHOU Chen(Department of Anesthesiology,Xuanwei Traditional Chinese Medicine Hospital,Xuanwei,Yunnan Province,655400 China;Department of Anesthesiology,Second Affiliated Hospital of Kunming Medical University,Kunming,Yunnan Province,650101 China)
出处
《中外医疗》
2019年第31期85-86,89,共3页
China & Foreign Medical Treatment
关键词
丙泊酚
七氟烷
老年肺癌
术后认知功能
影响
Propofol
Sevoflurane
Elderly lung cancer
Postoperative cognitive function
Influence
