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乐平市育龄妇女早期胚胎停育与甲状腺功能异常的关系 被引量:2

Relationship between early embryonic arrest and thyroxine dysfunction in women of childbearing age in Leping city
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摘要 目的分析乐平市育龄妇女早期胚胎停育与甲状腺功能异常的关系。方法选择2018年7月1日-2019年6月30日医院收治的住院妊娠分娩和早期胚胎停育患者140例,按照是否胚胎停育分为胚胎停育组和正常发育组各70例。2组患者均检查促甲状腺激素(TSH)水平,TSH异常者进一步检测甲状腺功能三项,比较2组TSH水平及妊娠终止时(胚胎停育组为胚胎停育时,正常发育组为分娩时)甲状腺功能三项水平。结果胚胎停育组孕6周及胚胎停育时TSH水平均高于正常发育组,差异均有统计学意义(P<0.05);胚胎停育组在胚胎停育时TSH水平高于正常发育组分娩时,三碘甲状腺原氨酸(T3)和甲状腺素(T4)水平低于正常发育组分娩时,差异均有统计学意义(P<0.05)。结论胚胎停育患者TSH水平显著异常,甲状腺功能相关指标亦异常,在孕6周即可表现。 Objective To analyze the relationship between early embryonic arrest and thyroxine dysfunction in women of childbearing age in Leping city.Methods 140 hospitalized pregnant women and early embryonic arrest who were admitted to hospital from July 1,2018 to June 30,2019 were selected,and they were divided into embryonic arrest group(70 cases)and normal development group(70 cases)according to whether the embryo was stopped or not.The level of TSH and the levels of thyroid function at the end of pregnancy(in the embryonic stop group,when the embryo was stopped,and in the normal development group at the time of delivery)in the two groups were compared.Results The level of TSH in the embryonic arrest group was higher than that in the normal development group at 6 weeks of gestation and when the embryo was stopped,the differences were statistically significant(P<0.05);The level of TSH in the embryonic arrest group was higher than that in the normal development group at the end of pregnancy,the levels of T3 and T4 in the embryonic arrest group were lower than that in the normal development group,the differences were statistically significant(P<0.05).Conclusion The level of TSH in patients with early embryonic arrest is significantly abnormal,and thyroid function related indicators are also abnormal,which can be expressed in pregnancy.
作者 吴琼霞 WU Qiongxia(Family Planning Section,Leping Maternal and Child Health Care Hospital,Jiangxi Province,Leping 333300,China)
出处 《临床合理用药杂志》 2019年第31期38-39,共2页 Chinese Journal of Clinical Rational Drug Use
基金 景德镇市科技计划项目(No:20183SFZC97)
关键词 育龄妇女 早期胚胎停育 甲状腺功能 功能异常 Women of childbearing age Early embryonic arrest Thyroxine function Dysfunction
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