摘要
目的探讨ST段抬高型心肌梗死(STEMI)患者急诊PCI植入三氧化二砷药物涂层支架(AVI)的安全性和有效性。方法诊断STEMI并在12h内行急诊PCI治疗的患者共47例[男26例,女21例,年龄(59.43±12.26)岁]。随机分为AVI组和Firebird组,植入相应支架。比较两组患者的手术安全性和随访观察主要心血管不良事件(MACE)发生情况。结果两组患者PCI成功率均为100%。两组患者在一般资料、靶血管特征、PCI情况等方面无明显统计学差异(均P>0.05)。两组患者住院期间未发现MACE事件,出院后平均随访4~36(25.74±7.35)个月,AVI组发生MACE事件5例,Firebird组发生1例,差异有统计学意义(P<0.05)。结论急性心肌梗死三氧化二砷药物涂层支架植入安全性好,但远期MACE发生率较高。
Objective To explore the efficacy and safety of arsenic trioxide-eluting stent(AVI)implantation in patients with ST-segment elevation myocardial infarction(STEMI).Methods 47(26 males,aged 59.43±12.26)patients with STEMI and underwent emergency percutaneous coronary intervention(PCI)were enrolled.They were randomly divided into AVI group and Firebird group,and implanted with corresponding stents.The safety of operation and major adverse cardiovascular events(MACE)during follow-up were analyzed.Results PCI was successful in both groups.There was no significant difference in baseline data,target vessel and PCI procedure between the two groups(all P>0.05).No MACE events were found during hospitalization.During follow-up 4-36(25.74±7.35)months,MACE occurred in 5 cases in AVI group and 1 case in Firebird group(P<0.05).Conclusion Implantation of AVI is safe in STEMI patients,but with higher MACE during long-term follow-up.
作者
沈剑耀
任品芳
张志诚
王翔
SHEN Jianyao;REN Pinfang;ZHANG Zhicheng(Department of Cardiology,Affiliated Central Hospital of Shaoxing University,Shaoxing 312030,China)
出处
《心电与循环》
2019年第6期494-497,共4页
Journal of Electrocardiology and Circulation
基金
绍兴市卫生计生科技计划项目(2017QN012)
关键词
心肌梗死
药物涂层支架
三氧化二砷
Myocardial infarction
Drug-eluting stent
Arsenic trioxide
