摘要
目的探讨小青龙汤加减治疗慢性阻塞性肺病急性加重(Acute Exacerbation of Chronic Obstructive Pulmonarydisease,AECOPD)的临床疗效。方法将2016年7月—2018年7月收治的64例AECOPD的患者作为研究对象,随机分为观察组和对照组,每组各32例,对照组给予西医常规治疗,观察组在对照组治疗的基础上采用小青龙汤剂加减治疗,比较两组患者治疗前后临床效果、血清炎性因子水平、免疫功能及肺功能。结果治疗后两组临床疗效、IL-6、TNF-α、FEV1、FVC及CD4+水平均显著高于治疗前(P<0.05),差异有统计学意义。治疗后观察组的临床疗效、IL-6、TNF-α、FEV1、FVC及CD4+水平高于对照组(P<0.05),差异有统计学意义。结论小青龙汤加减治疗AECOPD可以提高患者的临床疗效,调节机体免疫能力和炎性反应因子的释放,改善呼吸肌功能,值得临床推广应用。
Objective To explore the clinical effect of Xiaoqinglong Decoction on AECOPD.Methods A total of 64 patients with AECOPD admitted to our hospital from July 2016 to July 2018 were selected as research subjects and were randomly divided into observation group and control group,32 cases in each group.The control group was treated with routine western medicine and the observation group wasadministered with additional Xiaoqinglong Decoction on the basis of the treatment of the control group.The clinical effect,serum inflammatory factor level,immune function and lung function of the two groups were compared before and after the treatment.Results The clinical efficacy,IL-6,TNF-a,FEV1,FVC and CD4+levels of the two groups after treatment were significantly higher than those before treatment(P<0.05),and the difference was statistically significant.After treatment,the clinical efficacy,IL-6,TNF-a,FEV1,FVC,and CD4+levels of the observation group were significantly higher than those of the control group(P<0.05).Conclusion Xiaoqinglong Decoction can improve the clinical efficacy of AECOPD,regulate immunization of the body and the release of inflammatory cytokines,and improve the respiratory muscle function,and therefore it is worthy of clinical application.
作者
黄霞
廖安平
卢丹
HUANG Xia;LIAO Anping;LU dan(Xinyu Hospital of Traditional Chinese Medicine,Xinyu 338000,China)
出处
《现代医院》
2019年第11期1678-1681,共4页
Modern Hospitals
基金
新余市科技技术项目(20183090851)
关键词
小青龙汤
加减治疗
AECOPD
肺功能
临床疗效
免疫功能
炎性细胞因子
Xiaoqinglong Decoction
Addition and Subtraction Therapy
AECOPD
Pulmonary Function
Clinical Efficacy
Immune Function
Inflammatory Cytokines
