摘要
目的探讨过氧化氢联合碳酸氢钠溶液在经口气管插管新生儿中的应用效果。方法选择2018年1~12月在我院行经口气管插管治疗的60例新生儿为研究对象。按照随机数字表法将所有新生儿分为对照组和观察组,每组各30例。对照组应用碳酸氢钠溶液进行口腔护理,观察组联合应用过氧化氢和碳酸氢钠进行口腔护理。比较两组新生儿呼吸机相关性肺炎(VAP)发生率和口腔感染发生率,同时记录两组新生儿机械通气时间和住院时间。结果观察组VAP和口腔感染发生率分别为6.67%和0.00%,低于对照组(33.33%和26.67%),差异有统计学意义(P<0.05);观察组机械通气时间和住院时间为(8.33±2.04)h和(20.08±9.64)d,短于对照组[(13.81±2.81)h和(32.84±14.02)d],差异有统计学意义(P<0.05)。结论过氧化氢和碳酸氢钠联合口腔护理可降低经口插管新生儿细菌感染风险,预防口腔感染和VAP发生,并缩短住院时间。
Objective To explore the application effect of hydrogen peroxide combined with sodium bicarbonate soution on neonates undergoing oral intubation.Methods A total of 60 cases of neonates who received endotracheal intubation and ventilator ventilation in our hospital from January to December,2018 were selected as the study subjects.According to the random number table method,all newborns were divided into control group and observation group with 30 cases in each group.The control group was given oral care with sodium bicarbonate solution,while the observation group was given oral care with hydrogen peroxide and sodium bicarbonate.The infection rates of ventilator associated pneumonia(VAP)and oral infection,mechanical ventilation and hospitalization time were compared.Results The incidences of VAP and oral infection in observation group were 6.67%and 0.00%,lower than those in control group(33.33%and 26.67%),the differences were significant(P<0.05).The mechanical ventilation and hospitalization time in observation group were(8.33±2.04)h and(20.08±9.64)d,shorter than those in control group[13.81±2.81]h and([32.84±14.02])d,the differences were statistically significant(P<0.05).Conclusion Hydrogen Peroxide combined with Sodium Bicarbonate can reduce the risk of bacterial infection in neonates undergoing oral intubation,prevent oral infection and VAP,and shorten hospital stay.
作者
曹珍
杨翠
CAO Zhen;YANG Cui(Department of Neonatal,Ji′an Maternal and Child Health-Care Hospital,Jiangxi Province,Ji′an 343000,China)
出处
《中国当代医药》
2019年第32期245-247,共3页
China Modern Medicine
关键词
过氧化氢
碳酸氢钠
口腔护理
呼吸机相关性肺炎
住院时间
Hydrogen peroxide
Sodium bicarbonate
Oral care
Ventilator associated pneumonia
Hospitalization time
