摘要
目的观察忍冬藤痛风颗粒治疗湿热蕴结型痛风性关节炎的临床疗效及安全性。方法将84例患者依据就诊的先后顺序按1∶1比例随机分为对照组及观察组各42例,对照组予以别嘌醇片,观察组在对照组的基础上加服忍冬藤痛风颗粒,两组疗程均为1月。观察比较两组的临床疗效,中医证候积分,疼痛视觉评分(VAS),相关实验室指标,复发率及不良反应情况。结果观察组治疗总有效率(94.74%)显著的高于对照组(75.68%),同时观察组血尿酸、C反应蛋白、血沉及VAS评分较对照组明显降低,比较有统计学意义(P<0.05),治疗结束后5月随访患者满意度及复发率比较,观察组优于对照组(P<0.05)。结论忍冬藤痛风颗粒联合别嘌醇能够有效的缓解痛风性关节炎患者的临床症状,临床治疗效果优于单纯西药,值得推广使用。
Objective To observe the clinical efficacy and safety of Rendongteng Gout Granules in the treatment of damp-heat-concentrated gouty arthritis.Methods According to the order of treatment, 84 patients were randomly divided into control group and observation group with 42 cases each according to the order of treatment. The control group was treated with allopurinol tablets. The observation group was added to the control group based on the Rendongteng Gout Granules. Both groups were treated in January. Observe and compare the clinical efficacy, TCM syndrome score, pain visual score(VAS), relevant laboratory indicators, recurrence rate and adverse reactions.Results The total effective rate(94.74%) in the observation group was significantly higher than that in the control group(75.68%). At the same time, the serum uric acid, C-reactive protein, ESR and VAS scores in the observation group were significantly lower than those in the control group, which was statistically significant(P<0.05), The satisfaction rate and recurrence rate of patients in the follow-up period after the end of treatment were compared. The observation group was superior to the control group(P<0.05).Conclusion The combination of Rendongteng Gout Granules and allopurinol can effectively relieve the clinical symptoms of patients with gouty arthritis, and the clinical treatment effect is better than that of western medicine alone. It is worthy of promotion.
作者
李建国
谢兴文
李宁
徐世红
李鼎鹏
黄晋
LI Jian-guo;XIE Xing-wen;LI Ning;XU Shi-hong;LI Ding-peng;HUANG-Jin(Gansu Provincial Hospital of Traditional Chinese Medicine,Lanzhou Gansu 730050,China;Gansu Institute of Chinese Medicine,Lanzhou,Gansu 730050,China)
出处
《时珍国医国药》
CAS
CSCD
北大核心
2019年第10期2416-2418,共3页
Lishizhen Medicine and Materia Medica Research
基金
国家自然科学基金(地区)(81860864)
甘肃省兰州市科技局社会发展项目(2016-3-102)
甘肃省属科研院所基础条件建设专项(18JR2TA016)
国家中医药管理局中医临床研究基地业务建设专项(JDZX2015080)
甘肃省省级引导科技创新发展专项资金项目
甘肃省卫健委十三五重点专科培育项目
关键词
忍冬藤痛风颗粒
痛风
临床疗效
Rendongteng Gout
Gout particles
Gout
Clinical efficacy
