摘要
目的:优选萝卜硝的炮制工艺,为完善其质量标准提供参考。方法:采用正交试验考察萝卜硝炮制过程萝卜用量、共煮时间、结晶温度对炮制工艺的影响,以硫酸钠的含量与结晶得率(加权系数为6∶4)所得的总加权评分作为评价指标,优选萝卜硝的炮制工艺。并对萝卜硝进行薄层鉴别以保证其符合《四川省中药饮片炮制规范》的质量标准。结果:萝卜硝炮制最佳工艺为,皮硝加入萝卜汤(比例1∶1,萝卜汤为萝卜切片加水煎煮30min滤过所得)共煮15min后在0℃结晶24h。结论:优选工艺稳定可行,所得萝卜硝无水硫酸钠含量96%,符合规定。
Objective:To optimize the processing technology of radish mirabilite and provide reference for improving its quality standard.Method:The effects of radish dosage,co-boiling time and crystallization temperature on the processing technology of radish mirabilite were investigated by orthogonal test.Taking the total weighted score of sodium sulfate content and crystallization yield(weighted coefficient was 6:4)as evaluation index,the processing technology of radish mirabilite was optimized.The radish salts were identified by TLC to ensure that they met the quality standard of the Processing Standards of Sichuan Traditional Chinese Medicine Pieces.Result:The optimum processing technology of radishs mirabilite was that the radish soup was added to mirabilite(1:1,the radish soup was the filtrate obtained by boiling slices of radish with water for 30 minutes)and boiled for 15 minutes and then crystallized at 0℃for 24 hours.Conclusion:The optimum process is stable and feasible.The content of anhydrous sodium sulfate in radish soup is 96%,which meets the requirements.
作者
蒋淼
闵志强
林其越
何熙果
LIAO Bo
JIANG Miao;MIN Zhi-qiang;LIN Qi-yue;HE Xiguo;LIAO Bo(School of Pharmacy,Chengdu University of Traditional Chinese Medicine,Key Laboratory of Standardization for Chinese Herbal Medicine,Ministry of Education,National Key Laboratory Breeding Base of Systematic Research,Development and Utilization of Chinese Medicine Resources,Chengdu 611137,Sichuan)
出处
《中药与临床》
2019年第2期1-4,共4页
Pharmacy and Clinics of Chinese Materia Medica
基金
四川省教育厅项目（编号：18ZB0190）
四川省青年科技创新研究团队（编号：2017TD0001）
成都中医药大学科技发展基金项目（编号：ZRQN1646）
关键词
萝卜硝
炮制工艺
正交试验
Radish mirabilite
processing technology
orthogonal test
