摘要
目的评价静脉输注利多卡因对使用喉返神经监测专用气管导管行甲状腺手术患者术后咽痛的影响.方法择期全身麻醉下行甲状腺手术患者40例,ASA?I或II级,随机分为两组:利多卡因组(L组)和生理盐水组(S组),L组予诱导前静脉注射利多卡因1.5mg/kg,随后以2mg/(kg·h)的速度持续输注至手术结束,S组予以等体积生理盐水.记录入室安静后10min(T0)、气管插管前(T1)、气管插管后(T2)、拔管前(T3)的平均动脉压(MAP)及心率(HR),以及拔管后1h(T4)、6h(T5)、12h(T6)、24h(T7)咽痛评分以及患者对气管导管的耐受程度.结果与S组比较,L组T2及T3时患者平均动脉压MAP及HR均下降(P<0.05).L组T4及T5时咽痛评分≥3级者明显低于S组(P<0.05),同时L组气管耐受度优于S组(P<0.05).结论静脉输注利多卡因对于防治使用喉返神经监测专用气管导管行甲状腺手术患者术后咽痛有良好的防治作用.
Objective To evaluate the impact of intravenous infusion of lidocaine on sore throat after thyroid surgery which inserted the nerve integrity monitor(NIM)electromyographic(EMG)endotracheal tube.Methods Forty ASA I or II patients who underwent elective thyroid surgery under general anesthesia were randomly divided into lidocaine group(group L)and saline group(group S).Before anesthesia induction,group L was given lidocaine injection of 1.5 mg/kg,then with 2 mg kg^-1 h^-1 for infusion co the end of surgery.Group S received normal saline instead of lidocaine.The MAP and HR were recorded at 10 min after entering the operating room(TO),before endotracheal induction(T1),after endotracheal intubation(T2)and before extubation(T3).The endotracheal tube tolerance and sore throat scores were recorded lh(T4),6h(T5),12h(T6)and 24h(T7)after extubation.Results The MAP and HR were lower in group L than those in group S at T2 and T3(P<0.05).The sore throat scores in group L were significantly lower than those in group S at T4 and T5(P<0.05).In addition,the endotracheal tube tolerance of group L was better than group S(P<0.05).Conclusion Intravenous infusion of lidocaine has obvious preventive and therapeutic effects on postoperative sore throat after thyroid surgery.
出处
《浙江临床医学》
2019年第10期1385-1386,1389,共3页
Zhejiang Clinical Medical Journal
关键词
利多卡因
静脉输注
甲状腺切除术
咽痛
Lidocaine
Intravenous infusion
Thyroidectomy
Sore throat
