摘要
目的观察纳络酮在酒精中毒院前急救中的应用效果。方法选取彭州市人民医院急诊科院前急救的酒精中毒患者96例纳入研究,采用双盲随机法,分为对照组和观察组,各48例。对照组给予常规院前急救措施,观察组在对照组基础上应用纳洛酮。比较两组院前急救满意情况、血氧饱和度、血氧饱和度恢复至95%时间、清醒时间等临床效果及不良反应。结果观察组急救临床疗效为97.92%,明显高于对照组(79.17%,P<0.05)。治疗前两组血氧饱和度比较差异无统计学意义(P>0.05),但血氧饱和度恢复至95%时间、清醒时间上,观察组均短于对照组(P<0.05)。观察组院前急救总满意度为95.83%,明显高于对照组的(81.25%,P<0.05)。结论在酒精中毒患者的院前急救中应用纳洛酮可迅速缓解临床症状,能保证急救酒精中毒治疗效果且无明显的不良反应。
Objective To explore the application effect of naloxone in pre-hospital emergency treatment of alcoholism.Methods Ninety-six patients with alcohol toxicication receiving first aid before hospital in the emergency department of Pengzhou People's Hospital were divided into control group and observation group(48 cases each)by double-blind randomized method.The control group was given routine pre-hospital first aid measures,and the observation group was given naloxone on the basis of the control group.The first aid satisfaction,blood oxygen saturation,blood oxygen saturation recovery to 95%of the time,awake time and other clinical effects and adverse reactions were compared between the two groups.Results The clinical efficacy of first aid in the observation group was 97.92%,which was significantly higher than that in the control group(79.17%,P<0.05).There was no significant difference in blood oxygen saturation between the two groups before treatment(P>0.05),but the time of recovery of blood oxygen saturation to 95%was shorter in the observation group than in the control group(P<0.05).The total satisfaction of pre-hospital first aid in the observation group was 95.83%,which was significantly higher than that in the control group(81.25%,P<0.05).Conclusion The application of naloxone in the pre-hospital emergency treatment of patients with alcohol intoxication can rapidly relieve the clinical symptoms,ensure the effect of first-aid treatment of alcohol intoxication without obvious adverse reactions,and is worthy of being adopted and applied in the pre-hospital emergency treatment of alcohol intoxication.
作者
赵渝
杨英
ZHAO Yu;YANG Ying(Pengzhou People's Hospital Chengdu,Chengdou,Sichuan 611930,China)
出处
《大医生》
2019年第11期135-137,共3页
Doctor
关键词
纳络酮
院前急救
酒精中毒
应用效果
naloxone
pre-hospital first aid
alcohol intoxication
application effect
