摘要
The pre-B?tzinger complex(pre-B?tC) in mammalian brainstem is essential for the generation of respiratory rhythms.Most dynamic studies on the pre-B?tC neuron have been focused on its firing activities modulated by the ion conductances rather than that by the electromagnetic radiation or the external forcing current. In this paper, by adding the electromagnetic radiation and external forcing current to Park and Rubin’s model, we mainly investigate the influences of those two factors on the mixed bursting(MB) of single pre-B?tC neuron. First, we explore how the variation of external forcing current affects the MB patterns of the system with non-vanishing magnetic flux. We classify the MB patterns and show their dynamic mechanism through fast-slow decomposition and bifurcation analysis. Then, by modifying the feedback coefficient, we further analyze the sole effect of electromagnetic radiation on the firing activities of the system. Our results may be instructive in understanding the dynamical behavior of pre-B?tC neuron.
The pre-Botzinger complex(pre-BotC) in mammalian brainstem is essential for the generation of respiratory rhythms.Most dynamic studies on the pre-BotC neuron have been focused on its firing activities modulated by the ion conductances rather than that by the electromagnetic radiation or the external forcing current. In this paper, by adding the electromagnetic radiation and external forcing current to Park and Rubin’s model, we mainly investigate the influences of those two factors on the mixed bursting(MB) of single pre-BotC neuron. First, we explore how the variation of external forcing current affects the MB patterns of the system with non-vanishing magnetic flux. We classify the MB patterns and show their dynamic mechanism through fast-slow decomposition and bifurcation analysis. Then, by modifying the feedback coefficient, we further analyze the sole effect of electromagnetic radiation on the firing activities of the system. Our results may be instructive in understanding the dynamical behavior of pre-BotC neuron.
基金
Project supported by the National Natural Science Foundation of China(Grant Nos.11772069 and 11872003)
