摘要
目的观察活血通痹膏外用联合特定电磁波(TDP)治疗仪治疗类风湿关节炎(RA)痰瘀痹阻型的临床疗效。方法将889例RA痰瘀痹阻型患者按照随机数字表法分为3组。对照组298例予西医常规治疗;活血通痹膏外用组295例在对照组治疗基础上联合活血通痹膏外用治疗;联合组296例在活血通痹膏外用组治疗基础上联合TDP治疗仪治疗。3组均治疗15 d。比较3组治疗前后实验室指标类风湿因子(RF)、抗环瓜氨酸肽(抗-CCP)抗体、C反应蛋白(CRP)及红细胞沉降率(ESR)变化;比较3组治疗前后类风湿关节炎患者病情评价(DAS28评分)变化;比较3组治疗前后肿胀关节数、压痛关节数及疼痛视觉模拟评分法(VAS)评分变化。结果3组治疗后RF、抗-CCP抗体、CRP及ESR均较本组治疗前降低(P<0.05);3组治疗后RF、抗-CCP抗体、CRP及ESR比较差异均无统计学意义(P>0.05)。3组治疗后DAS28评分均较本组治疗前降低(P<0.05);活血通痹膏外用组、联合组治疗后DAS28评分均低于对照组(P<0.05);联合组治疗后DAS28评分低于活血通痹膏外用组(P<0.05)。3组治疗后肿胀关节数、压痛关节数及疼痛VAS评分均较本组治疗前降低(P<0.05);活血通痹膏外用组、联合组治疗后肿胀关节数、压痛关节数及疼痛VAS评分均低于对照组(P<0.05);联合组治疗后肿胀关节数、压痛关节数及疼痛VAS评分均低于活血通痹膏外用组(P<0.05)。结论活血通痹膏外用联合TDP治疗仪治疗RA痰瘀痹阻型,可改善患者临床症状,缓解患者关节肿胀、压痛,提高患者生活质量。
Objective To observe the clinical efficacy of external application of Huoxue Tongbi plaster combined with specific electromagnetic wave(TDP)therapeutic apparatus in the treatment of rheumatoid arthritis(RA)with blockage of phlegm and blood stasis type.Methods 889 RA patients were divided into three groups according to the random number table method.298 cases in control group were treated by routine western medicine.295 cases in Huoxue Tongbi plaster external application group were treated by Huoxue Tongbi plaster on the basis of the control group.296 cases in combined group were treated by TDP on the basis of the Huoxue Tongbi plaster external application group.All the three groups were treated for 15 days.The changes of rheumatoid factor(RF),anti cyclic citrulline polypeptide antibody(anti-CCP),C-reactive protein(CRP)and erythrocyte sedimentation rate(ESR)were compared before and after treatment in three groups.The changes of rheumatoid arthritis disease evaluation(DAS28 score)before and after treatment in three groups were compared,and the changes of swelling,tenderness joint number and pain visual analogue score(VAS)before and after treatment in three groups were compared.Results After treatment,RF,CRP,anti-CCP and ESR of the three groups were lower than that of the group before treatment(P<0.05).There was no significant difference in RF,CRP,anti-CCP and ESR of the three groups after treatment(P>0.05).After treatment,the DAS28 score of the three groups was lower than that of the group before treatment(P<0.05).The DAS28 score of the Huoxue Tongbi plaster external application group and the combined group was lower than that of the control group(P<0.05).The DAS28 score of the combined group was lower than that of the Huoxue Tongbi plaster external application group(P<0.05).The number of swollen joints,tenderness joints and the VAS scores in the three groups were lower than those in the group before treatment(P<0.05).The number of swelling joints,tenderness joints and the VAS scores in the Huoxue Tongbi plaster ex
作者
闫俊
柴旭兵
贺冬冬
叶楠
高亚亚
杨莹
赵星
侯西婵
刘立平
YAN Jun;CHAI Xubing;HE Dongdong(Department of Rheumatology and Immunology,The Fifth Hospital of Xi'an,Xi'an,Shaanxi 710082;不详)
出处
《河北中医》
2019年第8期1202-1206,共5页
Hebei Journal of Traditional Chinese Medicine
基金
陕西省中医管理局中医药科研课题(编号:15-jc024)
陕西省科学技术厅重点研发计划项目(编号:2017SF-245)
关键词
关节炎
类风湿
中西医结合疗法
Arthritis
rheumatoid
Integrated Traditional Chinese and western medicine therapy
