摘要
目的探讨经鼻高流量氧疗对急性呼吸衰竭患者血气分析结果和血流动力学的影响。方法选择2017年1月至2019年1月我院收治的急性呼吸衰竭患者82例为研究对象,采用随机数字表法分为对照组与观察组,每组41例。对照组患者采用常规面罩氧疗法治疗,观察组患者采用经鼻高流量氧疗法治疗,每天氧疗8 h以上,连续治疗2~3 d。比较两组患者治疗前(治疗前1 d)与治疗后(治疗后24 h)的血气分析结果、血流动力学指标、住ICU时间、住院时间以及不良反应发生情况。结果治疗前,两组患者的动脉氧分压(Pa O2)、动脉二氧化碳分压(Pa CO2)、心率、经皮氧饱和度(SpO2)和呼吸频率比较差异无统计学意义(P>0.05)。治疗后,两组患者的Pa O2均显著升高,Pa CO2均显著降低,观察组的Pa O2高于对照组,Pa CO2低于对照组;两组患者的心率、呼吸频率均显著降低,Sp O2均显著升高,观察组的心率、呼吸频率低于对照组,而SpO2高于对照组,差异有统计学意义(P<0.05)。观察组患者的住ICU时间和住院时间短于对照组,差异有统计学意义(P<0.05)。治疗期间观察组患者的不良反应发生率(2.44%)显著低于对照组(21.95%),差异有统计学意义(P<0.05)。结论经鼻高流量氧疗治疗急性呼吸衰竭患者临床效果良好,可有效改善患者的血气分析结果和血流动力学指标,减少并发症的发生,促进患者康复。
Objective To investigate the effect of high-flow nasal cannula on blood gas analysis and hemodynamics in patients with acute respiratory failure.Methods A total of 82 patients with acute respiratory failure admitted to our hospital from January 2017 to January 2019 were selected as the objects,and were divided into control group and observation group in accordance with random number table method,with 41 cases in each group.The control group received conventional mask oxygen therapy,while the observation group received the treatment of high-flow nasal cannula,with oxygen therapy for more than 8 hours per day,and continuous treatment for 2 to 3 days.Blood gas analysis results,hemodynamic indexes,length of ICU stays,hospital stays,and occurrence of adverse reactions before treatment(1 day before treatment)and after treatment(24 hours after treatment)were compared between the two groups.Results Before treatment,there was no statistically significant difference of comparison in partial arterial oxygen pressure(Pa O2),partial pressure of carbon dioxide in arterial blood(Pa CO2),heart rate,percutaneous oxygen saturation(SpO2)and respiratory rate between the two groups(P>0.05).After treatment,Pa O2 in both groups was significantly increased,while Pa CO2 was significantly decreased.Pa O2 of the observation group was higher than that of the control group,whereas Pa CO2 was lower than that of the control group.The heart rate and respiratory rate in both groups were significantly decreased,whereas SpO2 was significantly increased.The heart rate and respiratory rate of the observation group were lower than those of the control group,while SpO2 was higher than that of the control group,with statistically significant difference(P<0.05).The length of ICU stays and hospital stays in the observation group were shorter than those of the control group.The difference was statistically significant(P<0.05).The incidence of adverse reactions was significantly lower in the observation group(2.44%)than in the control group(21.95%),with st
作者
王晓玲
李宝红
尉家森
王玮
王立虎
WANG Xiaoling;LI Baohong;WEI Jiasen;WANG Wei;WANG Lihu(Department of Respiratory,Zhangye People′s Hospital Affiliated to Hexi University;Department ofInfection,Ganzhou District People′s Hospital,Zhangye 734000,Gansu province,China)
出处
《内科》
2019年第5期529-531,611,共4页
Internal Medicine
关键词
急性呼吸衰竭
经鼻高流量氧疗
血气分析
血流动力学
Acute respiratory failure
High-flow nasal cannula
Blood gas analysis
Hemodynamics
