摘要
目的:评估运用穴位注射疗法治疗妊娠剧吐的临床疗效。方法:通过计算机检索PubMed、Embase、生物医学文献数据库、CNKI、万方期刊数据库及维普数据库,收集关于运用穴位注射疗法或以穴位注射为主治疗妊娠剧吐的随机对照试验(RCT),采用Cochrane评价手册5.1对纳入的临床研究进行针对性的资料提取和质量评价,并采用RevMan5.3统计软件对提取的相关资料进行Meta分析。结果:总计纳入10篇文献,共834例患者,治疗组与对照组分别417例。Meta分析结果显示,穴位注射治疗妊娠剧吐的治愈率、有效率、尿酮改善情况均优于静脉补液,其中治愈率OR=4.18,95%CI(3.02,5.78),P<0.00001;有效率OR=4.95,95%CI(2.66,9.23),P<0.00001;并通过Egger’s检验分析纳入文章的发表偏倚,选取治愈率进行序贯分析,证明该Meta分析有意义。结论:穴位注射相对静脉补液、穴位注射联合静脉补液与单纯静脉补液相比,临床疗效较好。
Objective:To evaluate the clinical efficacy of acupoint injection in treating hyperemesis gravidarum.Methods:By computer retrieval,literatures of randomized controlled trials about acupoint injection in treating hyperemesis gravidarum were collected from Pubmed,EMbase,China Biology Medicine disc(CBMdisc),China National Knowledge Infrastructure(CNKI),WangFang and VIP databases.After data extraction and quality evaluation by using Cochrane Review Handbook 5.1,the eligible clinical trials underwent meta-analysis by using RevMen5.3 software.Results:A total of 10 articles met the inclusion criteria,including 834 patients with 417 cases in the treatment group and 417 cases in the control group.The meta-analysis showed that the cure rate,the effective rate and the ameliorative situation of urine ketone of acupoint injection were better than those of intravenous infusion in the treatment of hyperemesis gravidarum.In terms of the cure rate,OR=4.18,95%CI(3.02,5.78),P<0.00001.In terms of the effective rate,OR=4.95,95%CI(2.66,9.23),P<0.00001.Moreover,with the Egger's test,the publication bias were analyzed.The cure rate was chose to analyze the efficiency of the meta-analysis.Conclusion:Compared to single intravenous infusion,acupoint injection and acupoint injection plus intravenous infusion can produce a better clinical efficacy with less adverse reactions.
作者
林小杨
沈秋娴
庄礼兴
LIN Xiaoyang;SHEN Qiuxian;ZHUANG Lixing(Clinical Medical College of Acupuncture&Moxibustion and Rehabilitation,Guangzhou University of Chinese Medicine,Guangzhou 510405,China;The First Clinical Medical College of Guangzhou University of Chinese Medicine,Guangzhou 510405,China;The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405,China)
出处
《针灸临床杂志》
2019年第8期62-67,共6页
Journal of Clinical Acupuncture and Moxibustion
基金
庄礼兴广东省名中医传承工作室，编号:粤中医办函[2018]5号
