摘要
目的分析探讨在妊娠早期时母体的甲状腺功能异常对于妊娠结局的影响。方法前瞻性选取本院收治的152例妊娠早期合并甲状腺功能异常孕产妇,根据患者的情况将其分为甲亢组(50例)、甲减组(102例),同时将上述每组患者随机等分为治疗组和未接受治疗组两组,另选取同期在本院产科分娩的健康孕产妇150例作为对照组。在妊娠期间根据孕产妇的病情给予治疗组产妇相应的治疗,观察甲状腺疾病对于妊娠结局的影响情况和干预治疗的效果。结果妊娠期间未接受治疗组的甲亢组、甲减孕产妇与对照组在妊娠期糖尿病、贫血、妊高症等发生率方面有着明显的差异性(P<0.05),流产、早产、新生儿低体质量发生率方面与治疗组存在着明显的差异性,P<0.05,具有统计学意义。但在胎盘早剥、胎儿窒息发生率方面,三组患者则无明显的差异性,P>0.05,不具有统计学意义。结论在妊娠早期出现甲状腺异常将对其妊娠结局造成一定的不良影响,且并发症较多,应及时引起重视,给予孕产妇相应的治疗干预,尽可能在早期将甲状腺功能控制在正常水平,确保母婴的健康。
Objective To investigate the effect of maternal thyroid dysfunction on pregnancy outcome.Methods 152 pregnant women with thyroid dysfunction in early pregnancy were prospectively selected.The patients were divided into hyperthyroidism group(50 cases)and hypothyroidism group(102 cases).At the same time,each group was randomly divided into treatment group and non-treatment group.Another 150 healthy pregnant women who were delivered in department of obstetrics in our hospital during the same period were selected as control group.During pregnancy,according to the condition of pregnant,the treatment group was given corresponding treatment to observe the influence of thyroid disease on pregnancy outcome and the effect of intervention treatment.Results There were significant differences in the incidence of gestational diabetes,anemia and hypertension among the treatment group,non-treatment group and the control group(P<0.05).There were significant differences in the incidence of premature birth and low birth weight between the treatment group and non-treatment group(P<0.05).However,in the incidence of placental abruption and fetal asphyxia,there was no significant difference between the three groups with no statistical significance(P>0.05).Conclusion Thyroid abnormality in the early pregnancy will have a certain adverse impact on the outcome of pregnancy,and there are many complications,so we should pay more attention to pregnant women.We should give appropriate treatment and intervention in time,and we should control thyroid function as early as possible in order to ensure the health of mothers and babies.
作者
王娟
肖璐
WANG Juan;XIAO Lu(Department of Obstetrics,Maternal and Child Health Hospital,Xinjiang,Urumqi,830002,China)
出处
《新疆医学》
2019年第5期479-482,共4页
Xinjiang Medical Journal
