摘要
目的:探讨不同活跃度肱骨单纯性骨囊肿术后X线变化与其愈后关系,分析其临床意义。方法:收集2012年1月至2018年4月,我院手术治疗的儿童肱骨骨囊肿,分析活动期与静止期病例术后病灶部位X线变化情况与愈后的关系。活跃度分型及治疗疗效均采用Neer相关标准,行相关统计学分析。结果:共纳入66例,平均随访(22.05±4.34)个月;活动期38例,其中完全愈合6例,部分愈合13例,无反应15例,复发4例;静止期28例,其中完全愈合27例,部分愈合1例。两组的治愈率活动期50.0%(19/38)vs.静止期100%(28/28)(χ^2=19.660,P=0.000)。活动期治愈19例,静止期治愈28例,愈合时间(11.47±3.65)个月vs.(8.32±2.26)个月(t=1.779,P=0.082)。38个活动期病灶术后有16个病灶转变为静止期,其中16例获得治愈;而22例持续活动期病灶中治愈仅3例(χ^2=24.290,P=0.000)。结论:肱骨骨囊肿活动期病灶愈后较静止期差,活动期病灶术后向静止期病灶转变有较好愈后,临床应密切随访活动期病例,对骨囊肿的治疗应结合其影像学特征及变化行个体治疗。
Objective:To investigate the postoperative X-ray change of simple humeral bone cysts with different activity levels and its association with prognosis and clinical significance.Methods:The clinical data of children with humeral bone cysts who underwent surgical treatment in our hospital from January 2012 to April 2018 were collected,and the association between postoperative X-ray change of lesion and prognosis was analyzed in children in the active or latent stage of the disease.The Neer standard was used to evaluate activity level and treatment outcome,and a statistical analysis was performed.Results:A total of 66 children were enrolled and they were followed up for(22.05±4.34)months.Among these children,38 were in the active stage,among whom 6 achieved com-plete response,13 achieved partial response,15 had no response,and 4 experienced recurrence;28 were in the latent stage,among whom 27 achieved complete response and 1 achieved partial response.There was a significant difference in cure rate between the active group and the latent group[50%(19/38)vs.100%(28/28),χ^2=19.660,P=0.000].A total of 19 children in the active group and 28 children in the latent group achieved complete or partial response,and there was a difference in healing time between the active group and the latent group[(11.47±3.65)months vs.(8.32±2.26)months,t=1.779,P=0.082].Among the 38 active lesions,16 changed into latent lesions after surgery and all of them were cured,while among the 22 persistently active lesions,only 3 were cured(χ^2=24.290,P=0.000).Conclusion:Active lesions of humeral bone cysts tend to have a poor prognosis than latent lesions,and the active lesions that change into latent lesions after surgery tend to have a good prognosis.Patients in the active stage should be closely followed up in clinical practice,and individualized treat-ment should be given based on imaging features and changes.
作者
周荣
李明
刘星
翁刘其
郑超
周海
Zhou Rong;Li Ming;Liu Xing;Weng Liuqi;Zheng Chao;Zhou Hai(Department of Orthopaedics Ward One,Children’s Hospital of Chongqing Medical University,Ministry of Education Key Laboratory of Child Development and Disorders,China International Science and Technology Cooperation Base of Child Development and Critical Disorders,Chongqing Key Laboratory of Pediatrics)
出处
《重庆医科大学学报》
CAS
CSCD
北大核心
2019年第9期1176-1180,共5页
Journal of Chongqing Medical University
基金
国家临床重点专科建设资助项目(编号:国卫办医[2013]544)
关键词
骨囊肿
手术后
X线
愈后评价
bone cyst
postoperative period
X-ray
prognostic evaluation
