摘要
多囊卵巢综合征(polycystic ovary syndrome,PCOS)是导致妇女排卵障碍性不孕的最常见原因。对超重或肥胖的PCOS患者的不孕治疗,首选治疗方案是生活方式干预。二线治疗方案是促排卵治疗,其中一线用药为枸橼酸氯米芬和来曲唑,二线用药和方法包括促性腺激素、二甲双胍和腹腔镜下卵巢打孔术。辅助生殖技术适用于合并其他不孕因素的妇女,也是PCOS患者不孕治疗的三线治疗方案。
Polycystic ovary syndrome(PCOS)is the most common cause of anovulatory infertility.Lifestyle change is considered to be the first-line treatment for the management of infertile anovulatory PCOS women who are overweight or obese and the second-line treatment is ovulation induction,in which clomiphene citrate and letrozole are included for the first-line medication while gonadotrophins and metformin or laparoscopic ovarian surgery are included for the second-line medication and therapy.Assisted reproductive technology is recommended either as a third-line treatment or in the presence of other infertility factors.
作者
王荣敏
夏和霞
张炜
Wang Rongmin;Xia Hexia;Zhang Wei(Department of Gynecology,Obstetrics and Gynecology Hospital,Fudan University,Shanghai 200011,China;Department of Reproductive Endocrinology,Obstetrics and Gynecology Hospital,Fudan University,Shanghai 200011,China;Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases,Shanghai 200011,China)
出处
《上海医药》
CAS
2019年第21期11-16,共6页
Shanghai Medical & Pharmaceutical Journal
关键词
多囊卵巢综合征
不孕
促排卵
生活方式干预
polycystic ovary syndrome
infertility
ovulation induction
lifestyle change
