摘要
目的 探讨脑桥旁正中梗死患者发生进展的相关因素.方法 收集302例脑桥旁正中梗死患者的临床资料,根据美国国立卫生研究院卒中量表(NIHSS)评分的增加情况分成进展组92例和非进展组210例,回顾性分析两组患者的临床一般资料、实验室和影像学检查结果,入院时NIHSS分值,采用logistic回归分析危险因素.结果 进展组与非进展组比较,CRP增高者比例较高(35.29%比15.38%,P=0.007);中度动脉狭窄者比例较高(38.04%比24.76%,P=0.019);脑桥下部梗死(41.30%比29.52%,P=0.045),全部梗死(9.78%比3.33%,P=0.021)比例较高;NIHSS评分5~10分者比例较高(41.30%比29.05%,P=0.045).logistic回归分析显示高CRP、脑桥下部及全部梗死为发生进展的独立危险因素(OR=2.55、2.15).结论 感染、梗死部位等因素可能是影响脑桥旁正中梗死患者预后的风险预测因素.
Objective To analyze the risk factors for stroke progression in patients with paramedian pontine infarction.Methods A total of 302 patients with paramedian pontine infarction were enrolled,including 92 cases with progress(progress group) and 210 cases without progress(non-progress group).The predicting factors related to the risk of stoke progression were analyzed.Results The proportions of patients with increased serum C-reactive protein(CRP) level(35.29% vs.15.38%,P=0.007),with moderate arterial stenosis(38.04% vs.24.76%,P=0.019),with lower prontine infarction(41.30% vs 29.52%,P=0.045) or whole pontine infarction(9.78% vs 3.33%,P=0.021),with NIHSS score 5 to 10(41.30% vs.29.05%,P=0.045) in progress group were significantly higher than those in non-progress group.Logistic analysis showed that increasing CRP,lower or whole pontine infarction were the risk factors of stroke progression(OR=2.55 and 2.15) in patients with paramedian pontine inferction.Conclusion Infection and location ofpons infarction may affect the progression ofparamedian pontine infarction.
作者
邵敏洁
章立
周辰珩
金信春
金友雨
洪庆
SHAO Minjie;ZHANG Li;ZHOU Chenheng(Department of Neurology,Wenling First People’s Hospital,Taizhou 317500,China)
出处
《浙江医学》
CAS
2019年第20期2177-2180,共4页
Zhejiang Medical Journal
基金
台州市科技局资助项目(1702KY60)
关键词
脑桥梗死
基底动脉穿支病
卒中进展
风险预测
Pontine infarction
Basilar artery branch lesions
Stroke progression
Risk prediction
