摘要
冷诱导RNA结合蛋白(CIRP)是第1种在哺乳动物中发现的高度保守且被广泛研究的冷应激蛋白。从生物学的冷应激调控和临床医学角度分析,深入研究冷应激蛋白CIRP的功能及调节机制具有重要的科学价值。论文综述了冷诱导RNA结合蛋白在生殖发育、胚胎发育、神经调节、肿瘤等方面的研究进展,为鉴定CIRP的新功能提供理论依据。
Cold-inducible RNA-binding proteins(CIRP)are cold stress related proteins which were first identified in mammals.From the perspective of biological regulation of cold stress and clinical medicine,it has important scientific value to clarify the function and regulation mechanism of CIRP.In this paper,it mainly reviewed the research progress of CIRP in reproductive development,embryonic development,neuromodulation and tumor,providing theoretical basis for the identification of new functions of CIRP.
作者
周鸿淼
刘书东
吕慧捷
袁小伟
陈根元
ZHOU Hong-miao;LIU Shu-dong;L Hui-jie;YUAN Xiao-wei;CHEN Gen-yuan(Bayinguoleng Vocational and Technical College,Korla,Xinjiang,841000,China;Tarim University,Alar,Xinjiang,84300,China;Ninbo Institute of Science and Technology,Zhejiang University,Ningbo,Zhejiang,315100,China)
出处
《动物医学进展》
北大核心
2019年第10期75-78,共4页
Progress In Veterinary Medicine
基金
国家自然科学基金项目(41501307)
新疆维吾尔自治区2015高层次人才引进工程项目
兵团细毛羊种质资源保护项目
关键词
冷诱导RNA结合蛋白
冷应激调控
生殖发育
胚胎发育
功能
cold inducible RNA binding protein
regulation of cold stress
reproductive development
embryonic development
function
