摘要
目的探讨D二聚体(D-D)、N末端B型利钠肽原(NT-proBNP)与急性心肌梗死(AMI)患者经皮冠状动脉介入术(PCI)后亚急性支架内血栓形成(SST)的关系。方法选取2015年10月至2019年2月因AMI由在我院转广东省人民医院医院行PCI并发亚急性支架内血栓形成的AMI患者39例纳入血栓组;另选取同期在我院转广东省人民医院行PCI的AMI患者40例纳入对照组。分析D-D、NT-proBNP与AMI患者PCI术后SST的关系。结果血栓组血浆D-D和NT-proBNP水平显著高于对照组(P<0.05)。Spearman相关系数显示及晚期,血浆D-D和NT-proBNP原与AMI患者PCI术后SST呈显著正相关(P<0.05)。二分类Logistic回归分析显示,D-D、NT-proBNP是AMI患者PCI术后SST的独立危险因素。结论血浆D-D、NT-proBNP上升是引导AMI患者PCI术后SST的原因。
Objective To discuss the analysis of the relationship between D-dimer(D-D),N-terminal pro-B-typenatriuretie peptide(NT-proBNP)and percutaneous coronary intervention(PCI)for subacute stent thrombosis(SST)in patients with acute myocardial infarction(AMI).Methods 39 patients with AMI complicated with SST underwent PCI in our hospital from July 2015 to August 2018 were enrolled in the thrombus group.Another 40 patients with AMI undergoing PCI in our hospital were enrolled in the Control group.Analyze the relationship between D-D,NT-proBNP and PCI for SSTs in patients with AMI.Results Plasma levels of D--D,NT-proBNP in thrombus group were significantly higher than those in Control group(P<0.05).Spearman correlation coefficient showed that plasma D--D,NT-proBNP were positively correlated with PCI for SST in patients with AMI(P<0.05).Binary logistic regression analysis showed that D-D,NTproBNP were independent risk factors for PCI for SST in patients with AMI.Conclusion Plasma levels of DD,NT-proBNP rise to guide PCI for SST in patients with AMI.
作者
王海林
李如成
宁伟明
WANG Hai-lin;LI Ru-cheng;NING Wei-ming(Department of Cardiovascular Medicine,The People’s Hospital of Guangning,Zhaoqing,526300,China)
出处
《血栓与止血学》
2019年第5期769-771,共3页
Chinese Journal of Thrombosis and Hemostasis
