摘要
目前生物标志物的应用已经彻底改变了心血管疾病患者的筛查,其中应用最广泛的心血管生物标志物是利钠肽(应用于心力衰竭诊断和预后评估)及心肌钙蛋白(用于急性心肌梗死的诊断)。虽然生物标志物在诊断、预后评估和风险预测中的研究越来越多,但进入临床实际应用的生物标志物却为数不多。在该综述中,笔者根据心血管病理学的主要类别评估了不同生物标记物的应用并作对比分析。
Measurement of biomarkers has revolutionized the work-up of patients with suspected cardiovascular disease.The most widely used contemporary cardiovascular biomarkers are the natriuretic peptides in the diagnosis and prognosis of heart failure and cardiac troponins in the diagnosis of acute myocardial infarction.At present,although more and more biomarkers have been studied in diagnosis,prognosis assessment and risk prediction,only a few have made their way to clinical practice.In this review,the application of different biomarkers were evaluated and compared according to the main categories of cardiovascular pathology.
作者
李勇
宋嶶
LI Yong;SONG Wei(Department of Clinical Laboratory,the People′s Liberation Army Joint Service Support Unit 940 Hospital,Lanzhou,Gansu 730050,China)
出处
《国际检验医学杂志》
CAS
2019年第18期2276-2279,2301,共5页
International Journal of Laboratory Medicine
关键词
心血管疾病
生物标志物
应用
cardiovascular disease
biomarkers
application
