摘要
目的分析丙泊酚诱导麻醉后给予舒芬太尼在脑功能区手术唤醒麻醉中的作用。方法选取开封妇产医院2018-01—2019-01收治的90例脑功能区手术患者,根据不同麻醉方式将其分成2组各45例,观察组采用丙泊酚诱导麻醉后给予舒芬太尼,对照组采用丙泊酚诱导麻醉后给予瑞芬太尼,比较麻醉效果、麻醉期间2组患者的体征指标波动情况和唤醒情况,统计不良反应发生情况。结果观察组麻醉优良率为(95.56%),对照组为(91.11%),组间麻醉优良率对比无显著差异(P>0.05);2组患者插喉罩前(T 1)、插喉罩即刻(T 2)、插喉罩后5 min(T 3)、切皮时(T 4)的平均动脉血压(MAP)、心率(HR)明显低于本组基础值(T 0)(P<0.05);T 2时观察组MAP(73.83±7.10)mmHg明显高于对照组的(69.89±5.23)mmHg(P<0.05);T 0、T 1、T 2、T 3、T 4时2组的HR比较无明显差异,T 0、T 1、T 3、T 4时2组MAP比较无明显差异(P>0.05);2组唤醒时间对比差异无统计学意义(P>0.05);观察组苏醒时HR(91.23±15.62)次/min和苏醒时MAP(81.46±11.37)mmHg明显低于对照组的(98.57±7.67)次/min和(98.12±4.68)mmHg(P<0.05);观察组不良反应发生率(4.44%)明显低于对照组(17.78%)(P<0.05)。结论在脑功能区手术中应用丙泊酚诱导麻醉后给予舒芬太尼可有效改善唤醒质量,维持体征指标稳定,安全性可靠。
Objective To analyze the effect of propofol induced anesthesia with sufentanil on awakening anesthesia in brain functional area surgery.Methods Ninety cases of brain functional area surgery patients in our hospital between January 2018 and January 2019 were divided into two groups according to the different ways of anesthesia will all 45 cases,observation group with propofol sufentanil is administered after induction of anesthesia,after anesthesia with propofol induction were treated fentanyl,compare the anesthesia effect,the two groups of patients during anesthesia body-mass index volatility and awaken,statistical adverse reactions occur.Results The excellent and good rate of anesthesia was 95.56%in the observation group and 91.11%in the control group,and there was no significant difference between the two groups(P>0.05).The mean arterial blood pressure(MAP)and heart rate(HR)of the patients in the two groups were significantly lower than the basic values(T0)in this group(P<0.05).At T2,MAP(73.83±7.10)mmHg in the observation group was significantly higher than that in the control group(69.89±5.23)mmHg(P<0.05).There was no significant difference in HR between the two groups at T0,T1,T2,T3 and T4,and no significant difference in MAP between the two groups at T0,T1,T3 and T4(P>0.05).There was no significant difference in wake-up time between the two groups(P>0.05).In the observation group,HR(91.23±15.62)times/min and MAP(81.46±11.37)times/min were significantly lower than those in the control group(98.57±7.67)times/min and MAP(98.12±4.68)times/min(P<0.05).The incidence of adverse reactions in the observation group(4.44%)was significantly lower than that in the control group(17.78%,P<0.05).Conclusion The administration of sufentanil after propofol induced anesthesia in the operation of brain functional areas can effectively improve the quality of arousal,maintain the stability of physical signs,and is safe and reliable.
作者
甘美勤
雷雯淇
GAN Meiqin;LEI Wenqi(Kaifeng Maternity Hospital,Kaifeng 475000,China;West China Basic Medical College,Sichuan University,Chengdu 610000,China)
出处
《中国实用神经疾病杂志》
2019年第16期1833-1839,共7页
Chinese Journal of Practical Nervous Diseases
关键词
丙泊酚
脑功能区手术
舒芬太尼
唤醒麻醉
安全性
Propofol
Brain functional area surgery
Sufentanil
Arousal anesthesia
Safety
