摘要
目的探究B-lynch缝合术联合子宫填塞球囊压迫对凶险性前置胎盘患者血管内皮细胞迁徙及侵袭的影响。方法选取我院2015年1月至2018年6月收治的凶险性前置胎盘患者80例,其中采用常规出血处理和宫腔创面缝合的患者48例(对照组),采用B-lynch缝合术联合子宫填塞球囊压迫的患者32例(观察组),比较2组患者手术相关基本指标和术后不良情况,血清AFP、HCG和SFIt-1水平以及新生儿情况。结果观察组患者术中出血量、住院时间均显著少于对照组,血清AFP、HCG和SFIt-1水平在术后显著低于对照组,差异具有统计学意义(P<0.05);2组患者新生儿状况无显著差异,观察组患者不良情况发生率略低于对照组,差异无统计学意义(P>0.05)。结论B-lynch缝合术联合子宫填塞球囊压迫治疗能够减少凶险性前置胎盘患者术中出血,可降低血管内皮细胞的迁徙和侵袭能力,有利于患者恢复。
Objective To investigate the effect of B-lynch suture combined with uterine tamponade balloon compression on migration and invasion of vascular endothelial cell in patients of pernicious placenta previa.Methods Eighty patients with pernicious placenta previa were enrolled in our hospital from January 2015 to June 2018.The 48 patients in the control group underwent conventional hemorrhage management and uterine wound suture,while the 32 patients in the observation group were treated with B-lynch suture combined with uterine tamponade balloon compression.The basic and abnormal conditions,serum AFP,HCG and SFIt-1 levels,and neonatal status were compared between the two groups.Results Intraoperative bleeding and length of hospital stay were significantly lower in the observation group compared with the control group.The serum levels of AFP,HCG and SFIt-1 were significantly lower than those in the control group(P<0.05).There was no significant difference in neonatal status between the two groups.The incidence of adverse events was slightly lower in the observation group compared with the control group(P>0.05).Conclusion For patients with pernicious placenta previa,B-lynch suture combined with uterine tamponade balloon compression can reduce intraoperative hemorrhage the migration and invasion ability of vascular endothelial cells,which is beneficial to the recovery of patients.
作者
韩娟娟
郑琳
HAN Juan-juan;ZHENG Lin(Department of Gynaecology and Obstetrics,Wuxi Maternal and Child Health-Care Hospital,Wuxi Jiangsu 214000,China)
出处
《局解手术学杂志》
2019年第8期634-637,共4页
Journal of Regional Anatomy and Operative Surgery
