摘要
目的探究福州地区女性绝经前后诸证的中医证素特点及发病规律。方法收集308例患者,并与60例健康对照组比较,运用证素辨证方法 ,研究该病的病位证素与病性证素分布特点。结果 1福州地区女性绝经前后诸证的病位证素以肝、肾为主,尤以肝为发病的关键,肝的病理变化贯穿本病全程。脾、心、心神、胞宫的病变亦十分突出;2病性证素中阴虚、气滞、血虚的发生频率最高,是主要的病性证素。病理积分亦以阴虚为最高,其次为气滞和血虚。城镇患者肝、脾、心、心神的病变较农村显著,阴虚、气滞、痰、热、阳亢的病理变化明显高于农村患者;而农村患者肾的病变较城镇突出,血瘀、气虚、阳虚的病理变化明显高于城镇患者;3绝经前后诸证的证素特点受职业、文化程度、地域等多种因素的影响。结论福州地区女性绝经前后诸证发病有一定区域特点,肝为发病的关键,其病理变化贯穿本病全程。阴虚、气滞、血虚是主要的病性证素。证素特点受职业、文化程度、地域等多种因素的影响。
Objective To explore the characteristics of TCM syndrome elements and epidemic regularity of menopausal disorders women in Fuzhou. Methods 308 patients with menopausal disorders were collected, and 60 healthy people as control. The distribution characteristics of syndrome elements of disease location and disease nature were studied by the method of syndrome elements differentiation. Results The main syndrome elements of disease location of menopausal disorders women in Fuzhou were liver and kidney, especially for liver which was the key of pathogenesis, the pathogenic change of liver lasted whole course of the disease, and the pathology of spleen, heart, mind and womb were also significant. The first three syndrome elements of disease nature were Yin deficiency, Qi stagnation and bood deficiency. The pathological score of Yin deficiency was the highest, and the next were Qi stagnation and bood deficiency. The pathogenic changes of liver, spleen, heart and mind of urban women were more significant than those of rural women, and the pathogenic changes of Yin deficiency, Qi stagnation, phlegm, heat and Yang hyperactivities of urban women were higher than those of rural women. The pathogenic change of kidney of rural women was more significant than that of urban women, and the pathogenic changes of bood stasis, Qi deficiency and Yang deficiency of rural women were more significant. Conclusion The pathogenesis of menopausal disorders has certain regional characteristics in Fuzhou. Liver is the key of pathogenesis, and the pathogenic changes of liver last all through the process. Yin deficiency, Qi stagnation and bood deficiency are main syndrome elements of disease nature. The characteristics of syndrome elements of menopausal disorders were affected by occupation,culture, region and other factors.
出处
《福建中医药大学学报》
2014年第4期10-14,共5页
Journal of Fujian College of Traditional Chinese Medicine
基金
福建卫生厅中医药科研项目(WZZZ0908)
关键词
绝经前后诸证
证素
城镇女性
农村女性
menopausal disorders
syndrome elements
urban women
rural women