摘要
目的 探讨偏执型与非偏执型精神分裂症患者认知功能及精神症状的特征。方法 以美国精神障碍诊断与统计手册第 4版诊断标准 ,将 1 64例首发精神分裂症患者分为偏执型组 (1 1 9例 )及非偏执型组 (45例 ) ;分别进行韦氏成人智力量表、韦氏记忆量表、铁槽铁钉测验、利手测验、动作功能测验、手功能协调测验、连线测验A和B、威斯康星卡片分类测验及自编言语流利性测验 1 0项神经心理测查 ,并评定简明精神病评定量表 (BPRS)、修订的阴性症状评定量表 (SANS)、临床总体印象量表、功能总体评定量表 (GAF)。结果 (1 )认知功能 :偏执型组与非偏执型组各项认知功能的差异均无显著性 (均P >0 0 5)。 (2 )临床症状 :偏执型组与非偏执型组BPRS中的迟滞因子 [分别为 (5 2±1 3)分和 (7 0± 2 7)分 ]、思维障碍 [分别为 (1 3 9± 2 6)分和 (1 2 5± 3 0 )分 ]、SANS总分及各项因子分、GAF评分 [分别为 (37 1± 7 2 )分和 (32 7± 8 1 )分 ]的差异均有非常显著性 (均P <0 0 1 )。结论精神分裂症不同亚型的认知损害不具特征性 。
Objective Assess differences in cognitive functioning and psychotic symptoms between paranoid and non paranoid schizophrenic patients Methods 164 first episode schizophrenia patients were classified as paranoid type ( n =119) or non paranoid type ( n =45) according to DSM Ⅳ criteria and administered the Weschler Adult Intelligence Scale, Weschler Memory Scale, Grooved Pegboard Test, Finger Tapping Test, Edinburgh Handedness Test, Trail Making Tests A and B, Wisconsin Card Sort Test, motor function test, a hand coordination test, verbal fluency test, Brief Psychiatric Rating Scale, Chinese revision of the Scale for Assessment of Negative Symptoms, Clinical Global Impression Scale, and the General Assessment of Functioning Scale Results (1) There were no significant differences between the two groups on any of the cognitive tests (2)Patients with paranoid schizophrenia had significantly better overall function and more prominent thought disorder than non paranoid schizophrenic patients; negative symptoms in non paranoid schizophrenic patients were significantly more severe Conclusion There are no differences in the cognitive symptoms between different subtypes of schizophrenia, so these symptoms can not be used as diagnostic criteria for schizophrenic subtypes
出处
《中华精神科杂志》
CAS
CSCD
北大核心
2002年第4期241-244,共4页
Chinese Journal of Psychiatry
