摘要
目的探讨子宫内膜异位症在位子宫内膜的神经纤维含量及与疼痛的相关性。方法选取2013年4月至2014年4月就诊于深圳市妇幼保健院,并通过腹腔镜手术确诊的子宫内膜异位症患者55例作为研究组,根据VAS评分分为疼痛组(38例)和无痛组(17例),同期因子宫肌瘤或CINⅢ级行全子宫切除并且不伴有痛经的患者30例作为对照组,收集上述患者的在位子宫内膜,采用免疫组化比较两组患者的在位子宫内膜中神经纤维的表达。结果子宫内膜异位症疼痛组患者的在位子宫内膜中的神经纤维表达明显高于无痛组和对照组(P<0.05),并且内异症患者在位子宫内膜中神经纤维的表达与疼痛的严重程度有关(r=0.647,P<0.05)。结论在位子宫内膜中神经纤维的表达与子宫内膜异位症患者的疼痛相关。
Objective Objective To explore the nerve fibers quantity of eutopic endometrium in endometriosis and its relationship with pain. Methods Eutopic endometriums in endometriosis were prepared from 55 patients who were diagnosed with endometriosis under laparoscope( the study group)from April 2013 to April 2014 and 30 patients who were diagnosed as uterine fibroids or CIN III( the control group) at the same time. The patients in the study group were divided into two groups according to VAS score: 38 cases in pain group, and 17 cases in non-pain group. The expressions of eutopic endometriums in endometriosis were examined by immunohistochemical staining and analyzed statistically. Results The expressions of eutopic endometriums in endometriosis of patients in pain group were significantly higher than patients in non-pain group and the control group( P < 0. 05). The expressions of nerve fibers were positively correlated with the stage of pain( r = 0. 647, P < 0. 05).Conclusions The expressions of nerve fibers are close related to the pain in patients with endometriosis.
出处
《妇产与遗传（电子版）》
2015年第1期34-38,共5页
Obstetrics-Gynecology and Genetics (Electronic Edition)
