摘要
目的:通过对育龄妇女风疹抗体水平的调查,了解育龄妇女对风疹病毒免疫力状况,为科学接种疫苗提供理论根据。方法:采用定量间接ELISA方法对深圳市宝安区20～40岁1291例育龄妇女进行风疹病毒免疫力检测。结果:深圳市宝安区育龄妇女风疹病毒无保护力人群占到15.88％,明显高于80年代的调查结果;另外,20～29岁年龄组、30～40岁年龄组风疹病毒无保护力人群分别为19.4％,13.5％,两组比较统计学有显著差异(P<0.05)。结论:约有1/5生育活跃期育龄妇女对风疹病毒无保护力,孕前应加强风疹疫苗注射,以减少先天性风疹综合征的发生。
Objective:To investigate the immunity against rubella in women of childbearing age to provide the theoretical evidence for prevention of rubella and congenital rubella syndrome ( CRS). Methods; With indirect Enzyme linked immunosorbent assay (ELISA) Rubella IgG antibodies in serum specimen were detected in 1291 women from 20 to 40 years old in baoan district of Shenzhen. Results;The negative rates of RV -IgG was 15. 88% ,that was obviously higher than that of 1980s,also,there was highly significant difference on the negative rates of RV - IgG between women in the 20 to 29 years age group (19.4%) and 30 to 40 years age group (13.5% ). Conclusion :The women susceptible to rubella are suggested to vaccinated before pregnancy to reduce the impact of congenital rubella syndrome.
出处
《中国计划生育学杂志》
2002年第11期666-667,共2页
Chinese Journal of Family Planning
基金
本文为国家计划生育委员会出生缺陷干预工程项目
