摘要
目的探讨皮肤点刺试验、IgE血清过敏原和生物共振检测系统检测对结节性痒疹患者的过敏原检测的价值。方法选取中山大学附属第七医院2017年2月-2018年6月收治的结节性痒疹患者62例为病例组,另外选取同期于本院进行健康体检的人群60例为对照组。所有研究对象行皮肤点刺试验、IgE血清过敏原和生物共振检测系统检测。结果点刺试验检测结果显示,病例组中艾蒿、杨树、花生、猫毛、屋尘螨、粉尘螨、小虾阳性率均显著高于对照组,对比差异有统计学意义(P<0.05)。血清过敏原检测结果显示,病例组中葎草、屋尘、户尘螨、狗毛、猫毛、蟑螂、青霉、孢霉、总IgE阳性率均显著高于对照组(P<0.05)。生物共振检测系统检测结果显示,病例组中屋尘螨、粉尘螨、蟹类、虾类、牛肉、霉菌阳性率均显著高于对照组(P<0.05)。结论皮肤点刺试验和IgE血清过敏原检测对结节性痒疹患者过敏原检测具有十分重要的临床价值,皮肤点刺试验费用低廉,适合基层医院开展,而IgE血清过敏原检测则灵敏度高,但费用高,检测时间长。同时,生物共振检测系统检测也有一定的临床应用价值。
Objective To investigate the value of skin prick test, IgE serum allergen and bio-resonance detection system in the detection of allergen in nodular prurigo patients.Methods Totally 62 cases of prurigo nodosum were selected from February 2017 to February 2018 in our hospital as the case group. Another 60 cases were selected as the control group in the same period. All subjects underwent skin prick tests, IgE serum allergens and bio-resonance detection system.Results Prick tests showed that the positive rates of Artemisia, poplar, peanut, cat feline, house dust mite, dust mite and shrimp in the case group were significantly higher than those of the control group(P<0.05). Serum allergen test results showed that the positive rate of total IgE was significantly higher in the case group than that of the control group(P<0.05). The results of bio-resonance detection system showed that the positive rates of house dust mite, dust mite, crab, shrimp, beef and mold in the case group were significantly higher than those of the control group(P<0.05).Conclusion The skin prick test and IgE serum allergen test have very important clinical value in the detection of allergens in nodular prurigo patients. Prickling skin prick test is inexpensive and suitable for primary hospital, whereas IgE serum allergen test has high sensitivity, high cost, long testing time. At the same time, bio-resonance detection system testing also has some clinical value.
作者
朱林榆
冷少龙
ZHU Lin-yu;SHA Shao-long(Department of Dermatology,the Seventh Affiliated Hospital of Sun Yat-sen University,Shenzhen,Guangdong 518107,China)
出处
《医药论坛杂志》
2019年第9期15-18,共4页
Journal of Medical Forum
