摘要
目的探究520例小儿支气管哮喘急性发作的呼吸道病原学及临床特征。方法 520例小儿支气管哮喘急性发作患儿,均收集患儿鼻咽抽吸物标本进行呼吸道病原学检查,比较不同年龄患儿病原学检查结果和临床特征。结果<3岁患儿病毒、人博卡病毒(HBoV)检出率分别为81.82%、19.64%,均高于3~6岁患儿的68.16%、7.35%,差异具有统计学意义(P<0.05);不同年龄患儿呼吸道合胞病毒(RSV)、鼻病毒(HRV)、流感病毒(IFV)、副流感病毒(PIV)、细菌、卡他莫拉菌、流感嗜血杆菌、肺炎链球菌检出率比较差异均无统计学意义(P>0.05)。<3岁患儿合并肺炎占比为70.18%,高于3~5岁患儿的51.43%,差异具有统计学意义(P<0.05)。不同年龄患儿合并鼻炎史、湿疹史、家族史、血嗜酸性粒细胞≥5%、规律吸入糖皮质激素情况比较差异无统计学意义(P>0.05)。结论针对儿支气管哮喘急性发作患儿,呼吸道病毒感染为主要诱因,尤其对于<3岁患儿影响更大,且患儿常伴有肺炎情况,临床诊治需予以关注。
Objective To investigate the respiratory tract etiology and clinical characteristics in 520 children with acute attack of bronchial asthma. Methods There were 520 children with acute attack of bronchial asthma, and their nasopharyngeal aspiration specimens were collected for etiological examination of respiratory tract. The results of etiological examination and clinical characteristics of children of different ages were compared. Results The detection rate of virus and human Boca virus(HBoV) in children<3 years old were 81.82% and 19.64% respectively, which were higher than 68.16% and 7.35% in children aged 3-6 years, and the difference was statistically significant(P<0.05). There was no statistically significant difference in detection rates of respiratory syncytial virus(RSV), human rhinovirus(HRV), influenza virus(IFV), parainfluenza virus(PIV), bacteria, Moraxella catarrhalis, Haemophilus influenzae and streptowccus pneumoniae in children of different ages(P>0.05). The proportion of pneumonia in children <3 years old was 70.18%, which was higher than 51.43% in children aged 3-5 years old, and the difference was statistically significant(P<0.05). There was no statistically significant difference in history of rhinitis history, eczema, family, eosinophil >5% and regular inhalation of glucocorticoid among children of different ages(P>0.05). Conclusion For children with acute attack of bronchial asthma, respiratory virus infection is the main inducement, especially for children <3 years old, and children often accompanied by pneumonia, which clinical diagnosis and treatment should be paid attention to.
作者
魏文元
WEI Wen-yuan(Department of Pediatrics, Lingyuan Central Hospital, Lingyuan 122500, China)
出处
《中国现代药物应用》
2019年第20期18-19,共2页
Chinese Journal of Modern Drug Application
关键词
小儿支气管哮喘
急性发作
病毒感染
呼吸道合胞病毒
肺炎
Infantile bronchial asthma
Acute attack
Viral infection
Respiratory syncytial virus
Pneumonia
