摘要
目的探讨某三甲医院(以下简称"某院")妇科术后深静脉血栓形成患者抗凝药物应用的合理性评价,旨在为临床合理用药提供参考,同时探索一种妇产科临床药师深入临床开展药学服务的工作模式。方法回顾性分析2017年1月至2018年3月住院患者中有深静脉血栓形成诊断的19例患者的临床资料,统计患者基本情况、临床诊断、手术情况、常见危险因素、用药前后辅助检查情况以及用药情况,并通过用药合理性评价表来评价抗凝药物应用的合理性。结果根据合理性评价标准对19例病例进行评价,存在的不合理用药情况主要为药物选择不合理4例(21.05%)、用法用量不合理9例(47.37%)、监测指标不合理4例(21.05%)、用药疗程不合理13例(68.42%)、更换药物不合理5例(26.32%)。结论妇科抗凝药物的使用存在不合理现象,妇产科临床药师可以以此为切入点,通过开展知识宣教、用药建议、医嘱审核、处方点评等方式提高抗凝药物在临床的合理使用,也可通过对下肢深静脉血栓形成患者开展用药教育、定期随访等工作体现药师价值。
Objective To explore the rationale for the use of anticoagulant drugs in patients with deep vein thrombosis(DVT) in a teritary hospital(here in after referred to as "a hospital") and provide reference for clinical rational drug use;and explore a working model for clinical pharmacists in Department of Obstetrics and Gynecology. Methods We retrospectively analyzed the clinical data of 19 hospitalized patients diagnosed with DVT from January 2017 to March 2018, and summarized the basic conditions, clinical diagnosis, surgical conditions, common risk factors and auxiliary examination before and after medication administration. We also used domestic and foreign authoritative guidelines and drug instructions as the main evaluation criteria to evaluate the rationality of drug use. Results According to the evaluation criteria for rationality, among the 19 patients evaluated, the unreasonable drug use covered unreasonable drug selection in 4(21.05%), unreasonable dose in 9(47.37%), and unreasonable monitoring indicators in another 4 cases(21.05%). We found 13 cases(68.42%) had unreasonable medications, unreasonable drug replacements in 5(26.32%). Conclusion The clinical use of gynecological anticoagulant drugs may serve as the entry point for clinical pharmacists in the Department of Obstetrics and Gynecology. Clinical pharmacists may improve the rational use of anticoagulant drugs in clinical practice through education, drug advice, doctor order reviews, and prescription reviews, etc. The value of pharmacists can also be demonstrated through drug education and regular follow-up of patients with DVT.
作者
吴颖其
马宇辰
杨昭毅
童彤
沈爱宗
WU Ying-qi;MA Yu-chen;YANG Zhao-yi;TONG Tong;SHEN Ai-zong(Department of Pharmacy,the First Affiliated Hospital of University of Science and Technology of China,Hefei 230001;School of Pharmacy,Anhui Medical University,Hefei 230032)
出处
《中南药学》
CAS
2019年第10期1793-1797,共5页
Central South Pharmacy
基金
安徽省2017年度高等学校省级质量工程项目（No.2017jyxm1088）
安徽省2018年度高等学校省级质量工程项目（No.018jyxm0749,No.2018sxzx57）
关键词
合理性评价标准
深静脉血栓形成
抗凝药物
妇科
rationality evaluation criterium
deep vein thrombosis
anticoagulant drug
Department of Gynecology
