摘要
目的:探讨住院肝硬化患者的衰弱现状及其影响因素,为制定干预措施提供临床依据。方法:采用便利抽样的方法,应用卡罗来纳衰弱指数量表和步行测试对某三甲医院消化科住院的152例肝硬化患者进行横断面调查,并进行影响因素分析。结果:患者的衰弱指数为0.28±0.07,处于衰弱期38例(25.0%)、衰弱前期23例(15.1%)、健康状态91例(59.9%)。不同性别、既往跌倒史、疾病严重程度、学历和病因的患者之间的衰弱指数差异有统计学意义(P<0.05);相关性分析显示患者衰弱指数与年龄、中性粒细胞淋巴细胞比值呈正相关,与体质指数、血清白蛋白及步行速度呈负相关,且有统计学意义(P<0.05);多元回归分析显示,年龄、既往跌倒史和中性粒细胞淋巴细胞比值是肝硬化患者衰弱的影响因素,可解释因变量全部变异的41.8%。结论:年龄越大、有既往跌倒史及中性粒细胞淋巴细胞比值越高的肝硬化患者,其衰弱程度越高,医护团队应加强此类患者的护理管理,及时给予护理干预,降低患者的衰弱水平,减少跌倒等不良事件发生。
Objective:To describe the frailty status of hospitalized patients with cirrhosis,and to explore its influencing factors in order to provide clinical evidence for the development of clinical intervention measures.Methods:A cross-sectional survey was conducted on 152 patients with cirrhosis admitted to the department of gastroenterology in a top three hospital by means of a convenient sampling method using the Carolina frailty index and walking test,and its influencing factors were analyzed.Results:The patient’s frailty index was 0.28±0.07.There were 38 patients(25.0%)in the frail phase,23 patients(15.1%)in the pre-frail phase,and 91 patients(59.9%)in the robust state.There were statistically significant differences in frailty index between patients of different genders,previous falls history,disease severity,education background and etiology(P<0.05);correlation analysis showed that the frailty index was positive with age and neutrophil lymphocyte ratio,and negatively correlated with body mass index,serum albumin and walking speed(P<0.05).Multiple regression analysis showed that age,previous falls history and neutrophil lymphocyte ratio were debilitating in patients with cirrhosis,which could explain 41.8%of the total variation of the dependent variable.Conclusion:Elderlypatients with liver cirrhosis,previous falls and the higher the ratio of neutrophil lymphocytes have a higher degree of frailty,the health care team should strengthen the nursing management of such patients,and timely provide nursing interventions to reduce the patient’s frailty levels,and decrease the occurrence of adverse events such as falls.
作者
王莹
马颖丽
张楠
孙超
WANG Ying;MA Yingli;ZHANG Nan;SUN Chao(Tianjin Medical University General Hospital,Tianjin 300052)
出处
《天津护理》
2019年第5期542-546,共5页
Tianjin Journal of Nursing
关键词
肝硬化
衰弱
影响因素
跌倒
Cirrhosis
Frailty
Influencing factors
Falls
