摘要
细胆管癌(cholangiolocellular carcinoma,CLC)由于其特殊的细胞起源,具有肝细胞癌和胆管细胞癌的双重临床病理和影像学特点,由于惰性生长的特点、预后相对较好,其生长特点和临床特征明显有别于传统的肝内胆管癌(intrahepatic cholangiocarcinoma,ICC),是一种特殊类型的原发性肝脏恶性肿瘤.在细胞起源、临床病理特征、生长特点和预后等方面与传统意义的ICC是两种截然不同的疾病,但国内外有关ICC的研究中往往将两者混为一谈,没有明确的区分.本文就CLC临床病理特征进行综述,以期引发大家对这一问题的重视,并加强相关的研究.
Cholangiolocellular carcinoma(CLC),due to its special cell origin,has dual clinical and radiological features of hepatocellular carcinoma and cholangiocellular carcinoma,and has a relatively good prognosis due to the characteristics of inert growth.Its growth characteristics and clinical characteristics are obviously different from those of traditional intrahepatic cholangiocarcinoma(ICC).Therefore,CLC is a special type of primary liver malignancy.With regard to cell origin,clinical pathology,growth characteristics,and prognosis,CLC is a distinct disease from traditional hepatic cholangiocarcinoma;however,it is often confused with ICC in the relevant research worldwide.In this paper,we review the clinical and pathological characteristics of CLC to raise the attention to this problem and strengthen the relevant research.
作者
杨新伟
傅晓辉
张永杰
Xin-Wei Yang;Xiao-Hui Fu;Yong-Jie Zhang(Second Department of Biliary Tract Diseases,Eastern Hepatobiliary Surgery Hospital Affiliated to Naval Military Medical University,Shanghai 200438,China)
出处
《世界华人消化杂志》
CAS
2019年第18期1114-1117,共4页
World Chinese Journal of Digestology
基金
上海市卫生和计划生育委员会课题,No.20164Y0109
国家自然科学基金,No.81902940~~
关键词
细胆管癌
生物学特性
预后
Cholangiolocellular carcinoma
Biological feature
Prognosis
