摘要
目的探讨128层螺旋计算机断层扫描(MSCT)评价丹参多酚酸盐联合阿司匹林对冠心病心绞痛的患者左心功能的影响。方法将2016年1月-2018年6月间收治的500例冠心病心绞痛患者采用随机数表法分为观察组和对照组,每组各250例。对照组在常规治疗的基础上增加阿司匹林治疗,观察组在对照组基础上增加丹参多酚酸盐治疗。比较两组疗效,治疗前、治疗1月后评估患者血流动力学(全血黏度、血浆黏度、红细胞聚集指数),并采用MSCT评估患者左心功能[左心室舒张末期容积(EDV)、收缩期末容积(ESV)、每搏输出量(SV)、射血分数(EF)]。结果①治疗1月后,观察组治疗总有效率高于对照组(P<0.05);②治疗1个月后,两组全血黏度、血浆黏度、红细胞聚集指数均低于治疗前(P<0.05),观察组降幅大于对照组(P<0.05);③治疗1个月后,两组EDV、ESV均低于治疗前(P<0.05),两组SV、EF均高于治疗前(P<0.05),观察组变动幅度大于对照组(P<0.05)。结论128层MSCT可评估冠心病心绞痛患者左心功能,丹参多酚酸盐联合阿司匹林治疗冠心病心绞痛疗效良好。
Objective To explore the effects of 128-slice spiral computed tomography(MSCT)evaluation of salvianolate combined with aspirin on left ventricular function in patients with coronary heart disease and angina pectoris.Methods A total of 500 patients with coronary heart disease and angina pectoris admitted between January 2016 and June 2018 were divided into observation group and control group according to the random number table method,with 250 cases in each group.Control group was given aspirin on the basis of conventional treatment,and observation group was treated with salvianolate on the basis of control group.The efficacy was compared between the two groups,and the hemodynamics(whole blood viscosity,plasma viscosity,erythrocyte aggregation index)were evaluated before treatment and after 1 month of treatment.The left ventricular function indexes[left ventricular end-diastolic volume(EDV),end-systolic volume(ESV),stroke volume(SV),ejection fraction(EF)]were evaluated by MSCT.Results After 1 month of treatment,the total effective rate of treatment in observation group was higher than that in control group(P<0.05).After 1 month of treatment,the whole blood viscosity,plasma viscosity and erythrocyte aggregation index in the two groups were lower than those before treatment(P<0.05),and the decreases in observation group were greater than those in control group(P<0.05).After 1 month of treatment,the EDV and ESV in the two groups were lower than those before treatment(P<0.05),and the SV and EF in the two groups were higher than those before treatment(P<0.05),and the changes in observation group were greater than those in control group(P<0.05).Conclusion 128-slice MSCT can evaluate left ventricular function of patients with with coronary heart disease and angina pectoris,and salvianolate combined with aspirin has good efficacy in the treatment of angina pectoris.
作者
康晓军
王西辉
邱军杰
蒋伟
KANG Xiao-jun;WANG Xi-hui;QIU Jun-jie(Department of Cardiovascular,The Second Affiliated Hospital of Xi'an Medical University,Xi'an 710038,Shaanxi Province,China)
出处
《中国CT和MRI杂志》
2019年第11期58-60,80,共4页
Chinese Journal of CT and MRI
基金
陕西省科技厅基础项目2018SF-114
