摘要
目的:评估早期乳腺癌患者在放疗过程中焦虑水平的变化及其与摆位误差的关系。方法:选取初次放疗的早期乳腺癌患者65名,使用焦虑自评量表(SAS)、状态特质焦虑问卷[包括状态焦虑(SAI)和特质焦虑(TAI) 2个分量表]进行评估,放疗摆位误差(mm)由放疗时实时等中心验证片与治疗计划系统中的数字重建影像进行对比后获得。于初次放疗前(T1)、中期放疗前(T2)、末次放疗前(T3)进行3次评估。结果:患者在T1时SAS、SAI得分均高于T2和T3 (均P <0.05)。Wilcoxon秩和检验结果显示,T1与T2的高焦虑水平患者(SAS得分前27%的患者)的摆位误差均大于低焦虑水平患者(SAS得分后27%的患者)(均P <0.05),T3时两者的摆位误差差异无统计学意义(P> 0.05)。结论:早期乳腺癌患者初次放疗前焦虑水平最高,高焦虑水平可能与摆位误差较大相关。
Objective: To assess the trend of anxiety levels in patients with early breast cancer during radiotherapy and the relationship between anxiety symptom and the radiotherapy set-up errors.Methods: Totally 65 patients with early breast cancer who received initial radiotherapy were included.Assessment tools included Self-Rating Anxiety Scale(SAS) and State-Trait Anxiety Inventory [including State Anxiety Inventory(SAI) and Trait Anxiety Inventory(TAI)].The radiotherapy set-up error was obtained in millimeters by comparing the real-time isocratic verification film during radiotherapy with the digitally reconstructed radiograph in the treatment planning system.The patients were assessed three times before the first radiotherapy(T1),before the middle radiotherapy(T2),and before the last radiotherapy(T3).Results: The SAS and SAI scores of early breast patients were both higher at T1 than at T2 and T3(Ps < 0.05).Wilcoxon rank-sum test showed that patients with high level of anxiety at T1 and T2(the top 27% of patients with SAS scores) had greater set-up errors than patients with low level of anxiety(the last 27% of patients with SAS scores)(Ps < 0.05).There was no significant difference in the set-up errors between the patients with high and low levels of anxiety at T3(P > 0.05).Conclusion: Early breast cancer patients have the highest level of anxiety before the initial radiotherapy,and high anxiety level may be related to the set-up errors.
作者
高畅
陈吉祥
何毅
庞英
唐丽丽
GAO Chang;CHEN Jixiang;HE Yi;PANG Ying;TANG Lili(Key laboratory of Carcinogenesis and Translational Research ( Ministry of Education /Beijing),Department of Psycho-oncology, Peking University Cancer Hospital & Institute,Beijing 100142,China;Key laboratory of Carcinogenesis and Translational Research ( Ministry of Education /Beijing ),Department of Radiotherapy,Peking University Cancer Hospital & Institute,Beijing 100142,China)
出处
《中国心理卫生杂志》
CSSCI
CSCD
北大核心
2019年第11期812-815,共4页
Chinese Mental Health Journal
基金
北京市卫生与健康科技成果和适宜技术推广项目(2018-TG-48)
关键词
乳腺癌
焦虑
放疗摆位误差
breast cancer
anxiety
radiotherapy set-up error
